Transcription of PRODUCT INFORMATION CLOFEN - Medicines
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PRODUCT INFORMATION CLOFEN Baclofen NAME OF THE MEDICINE Active ingredient: Baclofen Chemical name: (3RS)-4-amino-3-(4-chlorophenyl)butanoic acid Structural formula: Molecular formula: C10H12 ClNO2 Molecular weight: CAS Registry No.: 1134-47-0 DESCRIPTION Baclofen is a derivative of gamma-aminobutyric acid (GABA). It is a white or almost white powder, slightly soluble in water, very slightly soluble in ethanol (96%), practically insoluble in acetone and in ether. It dissolves in dilute mineral acids and in dilute alkali hydroxides. Each CLOFEN 10 and CLOFEN 25 tablet contains baclofen 10 mg and baclofen 25 mg, as the active ingredient, respectively. The tablets also contain the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, calcium hydrogen phosphate, sodium starch glycollate, colloidal anhydrous silica, magnesium stearate.
CLOFEN – PRODUCT INFORMATION 2 Pharmacokinetics Absorption Baclofen is rapidly and completely absorbed from the gastrointestinal tract. Maximum concentrations of …
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