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*Correspondence: A. A. S. Ara jo. Departamento de Fisiologia, Universidade Federal de Sergipe-UFS. Av. Marechal Rondom, s/n -49000-100 - S o Crist v o - Sergipe-Brazil. E-mail: Journal of Pharmaceutical Sciencesvol. 46, n. 1, , 2010 Determination of the melting temperature, heat of fusion, and purity analysis of different samples of zidovudine (AZT) using DSCA driano Antunes Souza Ara jo1,*, Mar lia dos Santos Bezerra1, S lvia Storpirtis2, Jivaldo do Ros rio Matos31 Departament of Physiology, Federal University of Sergipe, 2 Departament of Pharmacy, Faculty of Pharmaceutical Sciences, University of S o Paulo, 3 Departament of Fundamental Chemistry, Institute of Chemistry, University of S o PauloThe Determination of chemical purity, melting range, and variation of enthalpy in the process of characterizing medicines is one of the principal requirements evaluated in quality control of the pharmaceutical industry.
Determination of the melting temperature, heat of fusion, and purity analysis of different samples of zidovudine (AZT) using DSC 39 F- fraction of sample melted at T
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