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ESBL、メタロ-β-ラクタマーゼ、AmpC型 -ラクタマーゼ過剰 …

250 56 10 2010 . Q esbl . - - AmpC - . Double Disc Synergy Test .. A .. 2.. 1 3 . extended - spectrum beta-lactamase esbl met- 1 . allo beta-lactamase MBL AmpC beta-lactamase - esbl . AmpC - - - . - . P. aeruginosa . Acinetobacter baumannii .. 3.. esbl MBL AmpC MRSA.. esbl MBL AmpC VRE .. 1.. esbl MBL AmpC - .. 18 . 251.. esbl esbl ChromID esbl . CTX CPDX esbl .. 1.. esbl . CLSI Clinical and Laboratory Standards Institute .. CLSI esbl 2 . 2.. 3 . 4 . esbl . E. coli K. MIC . pneumoniae K. oxytoca P. mirabilis 4 . Salmonella Shigella Citrobacter koseri . esbl .. CLSI 2010 document M100 -S20 . CLSI esbl . 4, 6, 7 . CTX . 94% MIC 8 g/ml 1 g/ml IPM MEPM. 5 . 4 g/ml 1 g/ml . esbl . CAZ CTX . esbl . MicroScan SIEMENS BD . esbl E-test esbl .. esbl . DDST Double Disc Synergy Test .. DDST esbl . AmpC - .. MIC AmpC Ser- ratia marcescens Enterobacter cloacae Citrobacter DDST esbl 1 freundii . 8, 9 . AMPC/CVA . CAZ CTX . 1.. 79 . 5 9 . 97% 94 100% CLSI DDST. DDST AmpC 2 . 3-aminophe- 20mm nylboronic acid class C.

Extended-spectrum beta-lactamaseESBL)、met-allo beta-lactamase(MBL)、AmpC beta-lactamase (AmpC)は、いずれもβ-ラクタム系薬を加水分解 する酵素(β-ラクタマーゼ)のひとつであり、日常検 査で高頻度に検出される腸内細菌やP. aeruginosa、

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  Spectrum, Bates, Extended, Esbl, Extended spectrum beta lactamases, Lactamases

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