Transcription of GUIDELINES FOR Extended Interval …
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GUIDELINES FOR Extended Interval …
140 - age)( IBW) x if female (72) (serum Cr) GUIDELINES FOR Extended Interval gentamicin /Tobramycin dosing / monitoring in ADULT patients Legacy Health System 2002 1. These GUIDELINES are NOT to be used in: Patients with severe renal disease (CrCl<30ml/min) or requiring dialysis. Use traditional kinetics to calculate an appropriate dose. Patients with gram positive infections where aminoglycoside is used for synergy Enterococcal Endocarditis (multiple doses/day more effective) Neonates or pediatric patients Pre-op surgical prophylaxis Patients with a history of allergy to aminoglycosides Patients with a history or signs of a hearing loss or vestibular dysfunction Deteriorating renal function 2. These GUIDELINES should be used with caution in: Patients with chronic ascites or serious liver disease Pregnancy (no data on fetal pharmacokinetics and toxicity) Patients with rapid clearance of drug ( cystic fibrosis, burns>20% of BSA) Patients who have received multiple courses of aminoglycosides in the past 3.
140 - age)( IBW) x 0.85 if female (72) (serum Cr) GUIDELINES FOR Extended Interval Gentamicin/Tobramycin Dosing/Monitoring in ADULT patients
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