Transcription of GUIDELINES FOR Extended Interval Gentamicin/Tobramycin ...
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GUIDELINES FOR Extended Interval Gentamicin/Tobramycin ...
140 - age)( IBW) x if female (72) (serum Cr) GUIDELINES FOR Extended Interval Gentamicin/Tobramycin dosing /Monitoring in adult patients Legacy Health System 2002 1. These GUIDELINES are NOT to be used in: patients with severe renal disease (CrCl<30ml/min) or requiring dialysis. Use traditional kinetics to calculate an appropriate dose. patients with gram positive infections where aminoglycoside is used for synergy Enterococcal Endocarditis (multiple doses/day more effective) Neonates or pediatric patients Pre-op surgical prophylaxis patients with a history of allergy to aminoglycosides patients with a history or signs of a hearing loss or vestibular dysfunction Deteriorating renal function 2. These GUIDELINES should be used with caution in: patients with chronic ascites or serious liver disease Pregnancy (no data on fetal pharmacokinetics and toxicity) patients with rapid clearance of drug ( cystic fibrosis, burns>20% of BSA) patients who have received multiple courses of aminoglycosides in the past 3.
140 - age)( IBW) x 0.85 if female (72) (serum Cr) GUIDELINES FOR Extended Interval Gentamicin/Tobramycin Dosing/Monitoring in ADULT patients
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