Transcription of HIGHLIGHTS OF PRESCRIBING INFORMATION
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HIGHLIGHTS OF PRESCRIBING INFORMATION These HIGHLIGHTS do not include all the INFORMATION needed to use KYLEENA safely and effectively. See full PRESCRIBING INFORMATION for KYLEENA. KYLEENA (levonorgestrel-releasing intrauterine system) Initial Approval: 2000 ----------------------------RECENT MAJOR CHANGES-------------------------- Dosage and Administration, Timing of insertion ( ) 3/2018 --------------------------- INDICATIONS AND USAGE -------------------------- Kyleena is a progestin-containing intrauterine system (IUS) indicated for prevention of pregnancy for up to 5 years. (1) ---------------------- DOSAGE AND ADMINISTRATION ---------------------- Release rate of levonorgestrel (LNG) is mcg/day after 24 days and declines to mcg/day after 5 years; Kyleena must be removed or replaced after 5 years. (2) To be inserted by a trained healthcare provider using strict aseptic technique.
FULL PRESCRIBING INFORMATION 1 INDICATIONS AND USAGE Kyleena is indicated to prevent pregnancy for up to 5 years. Replace the system after 5 years if continued use is desired. 2 DOSAGE AND ADMINISTRATION Kyleena contains 19.5 mg of levonorgestrel (LNG) released in vivo at a rate of approximately 17.5 mcg/day after 24 days.
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