Transcription of Industrial Production of Citric Acid
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Industrial Production of Citric Acid
Industrial Production of Citric AcidApplication of Citric acid : - Acidulant in food, confectionary, and beverage (75%)- Pharmaceutical (10%), soluble aspirin preparation- Industrial (15%): complexes with metals such as iron and copper to be stabilizer of oil and II Citric acid AND ALCOHOL , ,DEPARTMENT OF PHARMACUTICSSRM COLEGE OF PHARMACYSRMUNIVERITYW ikipediaCitric acid Production by Aerobic Bioprocesses-Microorganism: Aspergillus niger(mainly), Candida yeast (from carbohydrates or n-alkanes)- Citric acid Production is mixed growth associated, mainly take place under nitrogen and phosphate limitation after growth has requirements for high Production - Carbon source: molasses or sugar Na-ferrocyanide is added to reduce Iron ( ppm) and manganese (< ). - High dissolved oxygenconcentration- High sugar concentration-pH<2- 30 Production of Citric AcidBioreactor: batch or fed-batch (100m3)-5-25X106A. nigerspores/L may be introduced to the is provided to the fermenter by air sparging ( vvm)-Temperature is controlled by cooling : 50-100rpm to avoid shear damageon used to reduce substrate inhibition and prolong the Production phase one or two days after growth cessation.
Industrial Production of Citric Acid. Application of Citric Acid: - Acidulant in food, confectionary, and beverage (75%) - Pharmaceutical (10%), e.g. soluble aspirin
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