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Infrared Spectroscopy

Chapter 15. Infrared Spectroscopy Sherman Hsu, Separation Sciences Research and Product Development Mallinckrodt, Inc. Mallinckrodt Baker Division Summary General Uses Identification of all types of organic and many types of inorganic compounds Determination of functional groups in organic materials Determination of the molecular composition of surfaces Identification of chromatographic effluents Quantitative determination of compounds in mixtures Nondestructive method Determination of molecular conformation (structural isomers) and stereochemistry (geometri- cal isomers). Determination of molecular orientation (polymers and solutions). Common Applications Identification of compounds by matching spectrum of unknown compound with reference spectrum (fingerprinting). Identification of functional groups in unknown substances 247. 248 Handbook of Instrumental Techniques for Analytical Chemistry Identification of reaction components and kinetic studies of reactions Identification of molecular orientation in polymer films Detection of molecular impurities or additives present in amounts of 1% and in some cases as low as Identification of polymers, plastics, and resins Analysis of formulations such as insecticides and copolymers Samples State Almost any solid, liquid or gas sample can

Infrared (IR) spectroscopy is one of the most common spectroscopic techniques used by organic and inorganic chemists. Simply, it is the absorption measurement of different IR frequencies by a sample positioned in the path of an IR beam. The main goal of IR spectroscopic analysis is to determine the chemical functional groups in the sample.

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