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Introduction to Multivariate Genetic Analysis

Introduction to Multivariate Genetic AnalysisKate Morley and Fr hling Rijsdijk21st Twin and Family Methodology Workshop, March 2008 Aim and Rationale Aim: to examine the source of factors that make traits correlate or co-vary Rationale: Traits may be correlated due to shared Genetic factors (A) or shared environmental factors (C or E) Can use information on multiple traits fromtwin pairs to partition covariation into Genetic and environmental componentsExample 1 Why do traits correlate/covary? How can we explain the association? Additive Genetic factors (rG) Shared environment (rC) Non-shared environment (rE) Kuntsi et al.

Introduction to Multivariate Genetic Analysis Kate Morley and Frühling Rijsdijk 21st Twin and Family Methodology Workshop, March 2008. Aim and Rationale • Aim: to examine the source of factors that make traits correlate or co-vary • Rationale: Traits may be correlated due to shared

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