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렘수면행동장애의 치료 - JSM

24 Treatment of REM Sleep Behavior DisorderHye-Jin Moon, , Hyunwoo Nam, of Neurology, Boramae Hospital, Seoul National University, Seoul, KoreaREM sleep behavior disorder (RBD) is clinically characterized by the intermittent loss of normal skeletal muscle atonia during rapid eye movement (REM) sleep with the appearance of elaborate motor activity associated with dream mentation. Clonazepam, a sedating benzodiazepine, is currently regarded as the treatment of choice for RBD. In patients with contraindications to clonazepam, in those unresponsive to clonazepam, or in whom tolerance or serious side effects are observed, a therapeutic trial with melatonin up to 12 mg is recommended.

렘수면행동장애의 치료 Vol.6, No.1 / June, 2009 25 Table 1.Clonazepam treatment data Population studied (n) Dosage (mg) PSG Results Schenck CH. et al.8 Idiopathic RBD and RBD associated

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