Transcription of LysoTracker and LysoSensor Probes
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LysoTracker and LysoSensor Probes
MAN0001924 | MP 07525 Revision: Research Use Only. Not for use in diagnostic 1 Contents and storageMaterialAmountConcentrationStorag eStabilityLysoTracker and LysoSensor dyes20 vials, each containing 50 L1 mM stock solution in anhydrous DMSO 20 C Desiccate Protect from light Avoid freeze-thaw cycles Do not store in a frost-free freezer Store in single-use aliquots, if possibleWhen stored as directed, products are stable for at least 6 months* LysoTracker Deep Red5 vials, each containing 50 LLysoSensor Yellow/Blue dextran5 mg, lyophilized solidNA 20 C Desiccate Protect from lightWhen stored as directed, product is stable at least 1 year* If refreezing after use, seal the vial fluorescence excitation and emission, in nm: See Table 2, page and LysoSensor ProbesIntroductionLysoTracker ProbesWeakly basic amines selectively accumulate in cellular compartments with low internal pH and can be used to inves ti gate the biosynthesis and pathogenesis of ,2 The LysoTracker Probes are fluo res cent acido tropic Probes for labeling and tracking acidic organel les in live ,5 These Probes have several important features, including high selectivity for acidic organ elles and effective labeling of live cells at nanomolar concen tra tions.
Mar 09, 2015 · LysoTracker® and LysoSensor™ Probes | 2 LysoSensor™ pH Indicators For researchers studying the dynamic aspects of lysosome biogenesis and function in live cells, we offer LysoSensor™ probes—fluorescent pH indicators that partition into acidic organelles. The LysoSensor™ dyes are acidotropic probes that appear to accumulate in acidic organelles as …
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