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Mechanisms underlying uremic encephalopathy - SciELO

206 Rev Bras Ter Intensiva. 2010; 22(2):206-211 Mechanisms underlying uremic encephalopathyMecanismos b sicos da encefalopatia ur micaINTRODUCTIONAs a consequence of the numerous advances in early diagnosis and treat-ment of several diseases, critical care has developed as a subspecialty in all clini-cal disciplines engaged in life-threatening diseases. In neurology, this leads to an increase of neurological critical care units dealing with a broad spectrum of vascular infectious immunological and metabolic diseases and malignan-cies not only as primary diseases of the central and peripheral nervous systems and muscle but also as secondary affections caused by other organ or systemic diseases.(1)Acute renal failure (ARF) is a common and critical clinical entity, which af-fects around 5% to 7% of all hospitalized patients.

Mechanisms underlying uremic encephalopathy 207 Rev Bras Ter Intensiva. 2010; 22(2):206-211 pertension, fluid and electrolyte disturbances or drug tox-

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