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NSSG Chemotherapy Protocol

Lymphoma group This is a controlled document and therefore must not be changed or photocopied 1 of 8 ABVD Authorised by Lymphoma lead Dr. Graham Collins Published: July 2021 Review: May 2023 Version ABVD INDICATION Hodgkin lymphoma. For patients > 60 year old or with additional risk factors for bleomycin lung toxicity consider: - Omitting bleomycin entirely or - Only giving 2 courses containing bleomycin and omitting from the remaining cycles (especially in a fit older patient)11 Bleomycin should also be omitted from cycle 3A onwards if planning to receive 6 cycles of Chemotherapy and interim PET scan is negative (Deauville 1-3)10 TREATMENT INTENT Curative.

• Interim PET-CT scan should be performed at least 11 days after course 2B. Course 3A AVD should not be delayed whilst waiting for the result • If interim PET-CT scan was Deauville 1-3 then a contrast-enhanced CT of the neck, chest, abdomen and pelvis should be performed at the end of treatment, a PET is not usually required

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