Transcription of PARTICLE SIZE
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Example: confidence
PARTICLE SIZE
PARTICLE SIZEDISTRIBUTIONDrugDeliveryTechnologyMa y2009 Vol9No5xxINTRODUCTIO NThe need for par ticl e size control in the manufactureofpharmaceuticalsis becomingincreas ingl y apparen t asthe pharmaceuticalindust ry at tem pts to capi talize onsome APIs with less -than-i deal sol ubili ty ,signif icant advancesin drug del ivery have been made inwhich a finely di vi ded API, wit h the concom itantincr ease in specific surface area, has res ulted inincr eased bioav ailabi lit y. Preci se parti cle size controltechnolo gies hav e al so ass is ted in the de velopm ent ofdrug delivery platfor ms for the del ivery of amedi cament to the lung. As thes e trends have occu rred,the need for highly reproducible part icle sizeassessmenttechniqueshas grown si gnificantly in thepast decade.
PARTICLE SIZE DISTRIBUTION mathematicallyconvertedtonumber-weighted distributions,theconversionscanproduce misleadingartifacts. Disccentrifugemethodsrelyontheability
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