Transcription of Sample Size Calculations for Survival Analysis - ICSSC
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Sample Size Calculations for Survival Analysis - ICSSC
Sample size Calculations for Survival Analysis Mark A. Weaver, PhD. Family Health International Office of AIDS Research, NIH. ICSSC , FHI. Goa, India, September 2009. 1. 1. Design Considerations Will study enroll a fixed number of patients and follow each for some specified period of time? Or, will study continue until a sufficient number of events have been observed? Will any interim analyses be performed? 2. 2. Components in Sample size Calculations 1. Null hypothesis to be tested 2. Test statistic 3. Assumed effect size 4. size of the test (significance level, ). 5. Desired power 6. Sample size (in terms of number of events). 7. Probability of an event during study 8.
1 1 Sample Size Calculations for Survival Analysis Mark A. Weaver, PhD Family Health International Office of AIDS Research, NIH …
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