Transcription of SECTION 3 CHAPTER 18 Disease and Ulcerative Colitis
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SECTION 3 CHAPTER 18 Disease and Ulcerative Colitis
IntroductionUlcerative Colitis (UC) and Crohn s Disease (CD) arechronic inflammatory bowel diseases of unknown , both conditions usually begin gradually, butthey can start abruptly and sometimes even present asfulminant clinical course is characterized byexacerbations and spontaneous or drug-induced remis-sions. UC primarily affects the mucosa of the largebowel, while CD is a transmural Disease that can affectthe whole gastrointestinal tract. The various clinical pat-terns are reflected in the microscopic features observedin biopsies obtained from surgical specimens or duringendoscopy. Endoscopic mucosal biopsies will not showall the characteristic features of CD. Review of biopsies,in combination with clinical, laboratory, radiographicand endoscopic observations, is used for the diagnosis ofUC and CD and the differentiation from other condi-tions.
Introduction Ulcerative colitis (UC) and Crohn’s disease (CD) are chronic inflammatory bowel diseases of unknown cause. Clinically, both conditions usually begin gradually, but
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