Transcription of Selected Problems in Diagnosis Background to Thyroid …
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Selected Problems in Diagnosis Background to Thyroid …
1 Challenges in the Diagnosis of Thyroid Cancer An UpdateWilliam C. Faquin, , , Head and Neck PathologyMassachusetts General Hospital & Massachusetts Eye and Ear InfirmaryBoston, MASpeaker DisclosureNo Dislosuresto Faquin, , Problems in Diagnosis *Min. invasive follicular carcinoma* Variants of papillary Thyroid carcinoma * Poorly differentiated Thyroid carcinoma THYROIDB ackground to Thyroid Neoplasia2 Most common malignancy of endocrine system Annual incidence = 122,000 cases worldwide Young and middle-age adults More common in women (2-4x; 1:120 risk in ) >90% 10 year survivalTHYROID CARCINOMAThe Overdiagnosis of Thyroid CarcinomaAhn et al N Engl J Med (2014)15X increaseAggressive Thyroid Cancer Less focus on malignant vs benign (NIFT) More focus on identifying aggressive forms of Thyroid cancer How to define aggressive Thyroid carcinoma?
2 •Most common malignancy of endocrine system •Annual incidence = 122,000 cases worldwide •Young and middle-age adults •More common in women (2-4x; 1:120 risk in U.S.) •>90% 10 year survival THYROID CARCINOMA The Overdiagnosis of Thyroid Carcinoma Ahn et al N Engl J Med (2014) 15X increa se Aggressive Thyroid Cancer • Less focus on malignant vs benign (NIFT)
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