Transcription of Use of Enzymes in the Dissolution Testing of Gelatin ...
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Use of Enzymes in the Dissolution Testing of Gelatin ...
6 Dissolution Technologies | NOVEMBER 2014 STIMULI TO THE REVISION PROCESS Stimuli articles do not necessarily reflect the policies of the USPC or the USP Council of ExpertsUse of Enzymes in the Dissolution Testing of Gelatin Capsules and Gelatin -Coated Tablets Revisions to Dissolution <711> and Disintegration and Dissolution of Dietary Supplements <2040>Vivan A. Graya,b, Ewart Colea, Joan M. D. Riva Tomaa, Luigi Ghidorsia, Jian-Hwa Guoa, Jian-Hwa Hana, Feixue Hana, Christopher T. Hostya, Jianmei D. Kochlinga, Johannes Kraemera,b, Thomas Langdona, Steven R. Leinbacha, Gregory P. Martina,b, Steven M. Meyerhoffera, Richard C. Moretona,b, Krishnaswamy , Edward Shneyvasa, Jason A. Suggetta,b, Stephen Tindala, Madhusudan Vudathalaa, Hu Wanga, Om Anandc, Zongming Gaoc, Rakhi Shahc, Li Xiac, Joe Fotsoa, Munir A. Hussaina,b, Vi N. Schmidta, Tapash Ghoshc, Natalia Davydovad, William E.
Dissolution Technologeis | NOVEMBER 2014 7 specification. 2) The chapter recommends the use of pepsin when the medium is water or it has a pH less than 6.8. The pH for optimal activity of pepsin is up to a pH of 4; pepsin has
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