Transcription of Withdrawal from glucocorticosteroid therapy: …
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Withdrawal from glucocorticosteroid therapy: …
0021-7557/08/84-03/192 Jornal de PediatriaCopyright 2008 by Sociedade Brasileira de PediatriaREVIEWARTICLEW ithdrawal from glucocorticosteroid therapy: clinicalpractice recommendationsCr sio Alves,1 Teresa Cristina Vicente Robazzi,2 Milena Mendon a3 AbstractObjective:To present an up-to-date and practical review of how to safely withdraw glucocorticosteroid :A review of the published literature identified by searching the MEDLINE and LILACS databases(1997-2007), selecting the most representative articles on the of the findings:Three clinical situations may occur during glucocorticoid Withdrawal : adrenalinsufficiency secondary to negative feedback on the hypothalamic-pituitary adrenal (HPA) axis, steroid withdrawalsyndrome and relapse of the disease for which the glucocorticoids were prescribed.
contrast, clearance can be accelerated in patients on pheny-toin, phenobarbital or rifampicin.18 Syndromes associated with corticosteroid withdrawal
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