ACOG PRACTICE BULLETIN
reduced risk of uterine tachysystole with or without fetal heart rate (FHR) changes (18, 21). Misoprostol, a synthetic PGE 1 analogue, can be administered intravaginally, orally, or sublingually and is used for both cervical ripening and induction of labor. It currently is available in a 100-mcg (unscored) or a 200-
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