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AMIDES AND RELATED FUNCTIONAL GROUPS

AMIDES AND RELATED FUNCTIONAL GROUPS

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B. Nucleophilic-Electrophilic Reactions and Hydrolysis Because of the resonance delocalization of the NBEs in these compounds, amides are significantly less nucleophilic than amines, and generally less electrophilic than esters. Again, the low nucleophilicity of amides relative to amines is a result of the reduced availability of NBEs to

  Media, Reactions, Nucleophilic

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