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Chapter 3 Protecting Groups - USU

Chapter 3 Protecting Groups - USU

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Trimethylsilyl (TMS) Can be cleaved with K2CO3, MeOH or citric acid Triethylsilyl (TES) Can be cleaved with HOAc Triisopropylsilyl (TIPS) Possible for selective protection of 1° OH ... 1996, 37, 6029-6032) RNH2 1) SO2Cl2, MeCN 2) imidazole NaN3 N3 S O N O

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