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Chapter 3 Protecting Groups - USU

Chapter 3 Protecting Groups - USU

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14 (v) Benzylidene Common reagents for protection: PhCHO or PhCH(OMe)2 and acids (TsOH, PPTS, ZnCl2 etc) with removal of water Common reagents for deprotection: acids (TsOH, TFA, HCl etc) with addition of water * Can be selectively converted into Bn or Bz Examples: O HO OMe HO O O Ph NBS, CCl4 BaCO3, reflux O HO OMe HO Br BzO O HO OMe HO NBS ...

  Chapter, Acid

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