CHAPTER CARDIOVASCULAR DRUGS
duration of action. Thus glyceryl trinitrate and isosorbide dinitrate, 3., have a shorter onset time (< 5 minutes) in comparison to erythrityl tetranitrate and pentaerythritol tetranitrate (15→30 minutes). Similarly, the duration of action changes from 30-60 minutes for smaller molecules to 3-5 hours for the larger molecules. Metabolism
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