Of Warfarin
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An algorithm for managing warfarin resistance - ccjm
www.ccjm.orgwarfarin (Coumadin) to get their international normal-ized ratio (INR) into the therapeutic range. The cause of warfarin resistance can be either acquired (eg, poor compliance, drug interactions, dietary interactions) or hereditary, but the genetic mechanisms of warfarin resistance are not well understood. This review offers an
Guidelines For Antithrombotic Therapy
www.outcomes-umassmed.organticoagulant effect of warfarin is delayed, heparin is administered for rapid anticoagulation. When clinically indicated, conversion to warfarin should begin concomitantly with initiation of heparin therapy. After an overlap of three to five days, heparin can be discontinued when a therapeutic INR has been documented on two consecutive days.
FINAL Guidance on safe switching of warfarin to DOAC ...
elearning.rcgp.org.ukPrimary Care Cardiovascular Society CPA Primary care pharmacy Association www.pcpa.otg.uk UK CPA CLINICAL PHARMACY ASSOCIATION ROYAL PHARMACEUTICAL
Warfarin Dosing Protocol - UW Health
www.uwhealth.orgWarfarin Management CPG – Ambulatory Appendix A: Warfarin Management Dosing Tool – Adult – Ambulatory . Version 5.0 Created 10/28/2015 . Warfarin Initiation Dosing Protocol (Week 1) with INR Goal 2-3 Frequency of INR Monitoring After Initiation of Warfarin .
WARFARIN REVERSAL GUIDELINE - SurgicalCriticalCare.net
www.surgicalcriticalcare.netReversal of warfarin with Vitamin K should be reserved only for the most serious bleeding events or patients who will not be restarted on warfarin. Vitamin K should be administered either orally or intravenously (IV) only. Oral Vitamin K is the safest and most reliable route.
Figure 2: Guidelines for the management of patients on ...
www.bsg.org.ukStop warfarin for 5 days before endoscopy Check INR prior to procedure to ensure INR<1.5 Restart warfarin evening of procedure with usual daily dose Check INR 1 week later to ensure adequate anticoagulation Stop warfarin for 5 days before endoscopy Start LMWH 2 days after stopping warfarin Omit LMWH on day of procedure
Guidelines for the management of an elevated INR on ...
protocols.sonichealthcare.com• Omit warfarin, repeat INR the following day and adjust warfarin dose to maintain INR in the target therapeutic range • If bleeding risk is high* or INR >4.5, consider Vitamin K 1 1-2 mg orally or 0.5-1 mg IV Management of patients on warfarin therapy with high INR and no bleeding Clinical setting Recommendations INR higher than the
Warfarin Management - Adult - Inpatient Clinical Practice ...
www.uwhealth.orgmonitoring tools for most patients on warfarin therapy.4 Warfarin inhibits the reduction of vitamin K epoxide which limits the activation of vitamin K dependant clotting factors II, VII, IX and X. Warfarin is highly protein bound with a half-life of 36-42 hours. It is metabolized by the cytochrome P450 enzymes: 2C9, 1A2, and 3A4.2