Search results with tag "Protecting groups in organic synthesis"
Protecting Groups in Organic Synthesis-1 Ready
www.utsouthwestern.eduProtecting Groups in Organic Synthesis-1 Ready Protecting groups are a sad fact of synthetic chemistry They are usually needed, but rarely desired Many syntheses have stalled because of trouble putting on or removing protecting groups 4 basic …
PROTECTING GROUPS IN ORGANIC SYNTHESIS
profiles.uonbi.ac.keProtecting Groups in Organic Synthesis 6 The commonly encountered functional groups in organic synthesis that are reactive to nucleophilic or electrophilic reagents whose selective transformation may present challenges do regularly require deactivation by masking with a protecting group.
Protecting Groups in Organic Synthesis-1 Ready
www4.utsouthwestern.eduto avoid protecting groups Protecting Groups for Alcohols 4 major classes: silyl ethers, ethers, esters, acetals Silyl Ethers Si O TMS Si O TES Si O ... Lewis Acid: S N1 mechanism Na/NH 3 O R_ HO R 2e-, H+ CrO 3: via benzoate O R O R HO CrO R 3-OH O ... Protecting Groups in Organic Synthesis-8 Ready acetal protection of diols …