AviAn influenzA vAccine producers And suppliers for ...

1 AviAn influenzA vAccine producers And suppliers for poultry (June 2009) This list is to provide information on vAccine manufacturers and suppliers . The manufacturers and their vaccines are not necessarily endorsed by FAO and it is the country s responsibility that independent quality assurance/quality control for safety, purity, potency, and efficacy parameters be established. laboratoryAffiliation strainsubtypevaccine categoryWeb sitecommercial nameMonovAlent inActivAted H5n2 vAccinesAvimex laboratories, MexicoA/Chicken/Mexico/232/94/CPAH5N2 , LPinactivated, oil influenzA H5 Boehringer Ingelheim Vetmedica de , MexicoBoehringer Ingelheim Vetmedica, GmBH, Ingelheim am Rhein, GermanyA/Chicken/Mexico/232/94/CPAH5N2 , LPInactivated, oil Volvac AI KVCeva Mexico"Ceva Sant Animale SA La Ballastiere 33501 Libourne, France"A/Chicken/Mexico/232/94/CPAH5N2 , LPinactivated, oil Dodge Animal HealthFort Dodge Animal Health, Overland Park, USAA/TY/California/20902/2002H5N2, LPinactivated, oil adjuvantAvian influenzA vAccine , H5N2 SubtypeChengdu Jianghua Bioproducts Ziyang City, Sichuan province, ChinaJianghua GroupA/Turkey/England/N-28/73H5N2, LPInactivated, oil Yongshun Bio-pharm , Quangdong Province, ChinaA/Turkey/England/N-28/73H5N2, LPInactivated.

2 Oil adjuvantHarbin Veterinary Research Institute, Harbin, Heilongjiang province, ChinaNational Veterinary Research Institute and National Reference laboratory for AviAn influenzA , Harbin, Heilongjiang province, ChinaA/Turkey/England/N-28/73H5N2, LPInactivated, oil Animal HealthA/Turkey/Minnesota/3689-1551/81H5N 2 Inactivated, oil Biken Laboratories, Inc, JapanH5N1 Inactivated, oil BIKEN" POULSAVER AIIntervet, Boxmeer, The NetherlandsA/duck/Potsdam/1402/86H5N2, LPInactivated, oil influenzA H5N2 Intervet, MexicoIntervet, Boxmeer, The NetherlandsA/Chicken/Mexico/232/94/CPA H5N2, LPInactivated, oil influenzA H5 Investigaci n Aplicada (IASA), Tehuacan, Puebla, MexicoA/Chicken/Mexico/238/94/CPAH5N2, LPInactivated, oil AILaprovet , Tours, Cedex 2, France A/Chicken/Mexico/232/94/CPAH5N2, LPInactivated, oil Yikang Bioengineering Co., LtdLiaoyang City, Liaoning Province, ChinaA/Turkey/England/N-28/73H5N2, LPInactivated, oil adjuvantNanjing Merial Animal Products Co., Ltd Nanjing City, Jiangsu province, ChinaJoint Venture Merial China and China Animal Husbandry GroupA/Turkey/England/N-28/73H5N2, LPInactivated, oil adjuvantMedion, IndonesiaA/Turkey/England/N-28/73H5N2, LPInactivated, oil adjuvantMedivac AIQilu Animal Health Products Factory, Ji'nan City, Shandong province, ChinaA/Turkey/England/N-28/73H5N2, LPInactivated, oil Yebio Bioengineering Co.

3 Ltd Qingdao City, Shandong province, ChinaNational Animal Quarantine Institute of the Ministry of AgricultureA/Turkey/England/N-28/73 H5N2, LPInactivated, oil , IndonesiaA/Turkey/England/N-28/73 H5N2, LPInactivated, oil adjuvantVaksiflu N2 Zhaoqing Dahua agriculture Bio-pahrm , Zhaoqing City, Guangdong, ChinaVeterinay College of Southern China Agriculture UniversityA/Turkey/England/N-28/73H5N2, LPInactivated, oil strainsubtypevaccine categoryWeb sitecommercial nameAviAn influenzA vAccine producers And suppliers for poultry FAO/EMPRES February 2009 Page 2 Zhengzhou Bio-pharm Co. Ltd Zhengzhou City, Shandong province, ChinaChina Animal Husbandry GroupA/Turkey/England/N-28/73H5N2, LPInactivated, oil adjuvantInfluenza and NDIntervet, MexicoH5N2 Nobilis influenzA H5+NDMonovAlent inActivAted H5n9 vAccinesBiomune vaccines, Lenexa - Kansas, USACeva Sant Animale SA A/Turkey/Wisconsin/68 H5N9, LPInactivated, oil adjuvantLayermune AIV H5N9 Merial Italia SpaMerialA/Turkey/Wisconsin/68H5N9, LPInactivated, oil Flu H5N9 Merial Italia SpaMerialA/chicken/Italy/22A/98 H5N9, LPInactivated, oil adjuvant Gallimune Flu H5N9 Intervet, Boxmeer, The NetherlandsIntervetA/duck/Potsdam/2243/8 4H5N6, LP inactivated, oil influenzA H5N6 Fort Dodge Animal HealthFort Dodge Animal Health, Overland Park, USAA/TY/Wisconsin/1968H5N9, LPinactivated, oil adjuvantAvian influenzA vAccine , H5N9 SubtypeFort Dodge Animal HealthFort Dodge Animal Health, Overland Park, USAA/CK/Italy/22A/H5N9/1998H5N9, LPinactivated.

4 Oil adjuvantPOULVAC Flufend i-AI H5N9 MonovAlent inActivAted H5n1 vAccinesHarbin Veterinary Research Institute, Harbin, Heilongjiang province, ChinaA/Goose/Guangdong/1996H5N1, HPInactivated, oil , IndonesiaA/Ck/Legok/2003H5N1, HPinactivated, oil adjuvantMedivacPusvetma, IndonesiaMinistry of Agriculture, Republic IndonesiaA/Ck/Legok/2003H5N1, HPinactivated, aluminiumhydroxydAfluvetVaksindo, IndonesiaA/Ck/Legok/2003H5N1, HPinactivated, oil adjuvantVaksiflu AIVeterinary Research Institute, Lahore, PakistanMinistry of Food, Agriculture and Livestock, Province of Punjab, PakistanA/Ck/Mansehra/2006H5N1, HPinactivated, oil adjuvantAI-H5 VaccineSindh vAccine Production Centre, Karachi, PakistanMinistry of Food, Agriculture and Livestock, Province of Sindh, PakistanA/Ch/Mansehra/2006H5N1, HPinactivated oil adjuvantAI-H5 VaccineOttoman Pharmaceuticals, Lahore, PakistanPrivate companyH5N1, HPinactivated oil adjuvantFluvac-H5 Biolabs (pvt) Ltd, Islamabad, PakistanPrivate companyA/Ch/Mansehra/2006H5N1, HPinactivated oil adjuvantBiovac-AIMonovAlent reverse genetics H5 vAccinesFort Dodge Animal Health, Overland Park, USArg-A/ck/VN/C58/04 with N3 gene from A/Duck/Germany/1215/73 (H2N3) and six internal genes from PR8 vAccine strainH5N3 RGreverse genetic, oil Flu Fend H5N3 RGHarbin Veterinary Research Institute, Harbin, Heilongjiang province, ChinaA/Goose/Guangdong/1996 (Re-1), BHG/QH/05 (Re-3); DK/AH/06 (Re-5) or CK/SX/06 (Re-4) and PR8 backboneH5N1, RGreverse genetic, oil Yebio Bioengineering Co.

5 Ltd Qingdao City, Shandong province, China A/Goose/Guangdong/1996 (Re-1), BHG/QH/05 (Re-3); DK/AH/06 (Re-5) or CK/SX/06 (Re-4)and PR8 backboneH5N1, RGreverse genetic, oil adjuvantZhengzhou Bio-pharm Co. Ltd Zhengzhou City, Shandong province, ChinaChina Animal Husbandry Groupreverse genetic virus from A/Goose/Guangdong/1996 (re-1), BHG/QH/05 (Re-3); DK/AH/06 (Re-5) or CK/SX/06 (Re-4)and a PR8 vAccine strain backboneH5N1 RGreverse genetic, oil adjuvant laboratoryAffiliation strainsubtypevaccine categoryWeb sitecommercial nameAviAn influenzA vAccine producers And suppliers for poultry FAO/EMPRES February 2009 Page 3 Nanjing Merial Animal Products Co., Ltd Nanjing City, Jiangsu province, ChinaJoint Venture Merial China and China Animal Husbandry GroupA/Goose/Guandong/1996 and PR8 backboneH5N1, RGreverse genetic, oil adjuvantIBP-Shigeta, Bogor, IndonesiaPT IPB Shigeta Animal Pharmaceuticalsreverse genetic virus from A/Ck/Legok/2003 H5N1 RGreverse genetic, oil Bird Close vAccines WitH H5 coMponentHarbin Veterinary Research Institute, Harbin, Heilongjiang province, ChinaAvian pox virus with a cDNA insert of the H5 and N1 gene from A/Goose/Guangdong/1996H5 derived from H5N1 HPLive recombinant, freeze Veterinary Research Institute, Harbin, Heilongjiang province, ChinaLive Newcastle disease virus (LaSota) and H5 A/Barheaded goose/Qinghai/3/2005H5N1 HPLive recombinant NDV vectored H5, freeze Select (US)

6 MerialFowlpox virus with cDNA insert of H5 gene from A/Turkey/Ireland/83 H5 derived from H5N8 LPLive recombinant, freeze dried, subcutaneous AIV-H5 produced in US, AtlantabivAlent inActivAted Ai vAccinesCeva, MexicoCeva Sant Animale SA (France)A/Chicken/Mexico/232/94 H5N2 LP + La Sota NDVinactivated, oil adjuvantNEW-FLU-KEMFort Dodge Animal HealthFort Dodge Animal Health, Overland Park, USAA/CK/Italy/22A/H5N9/1998&A/CK/Italy/1 067/H7N1/1999H5N9/H7N1 bivalentOil adjuvantPOULVAC Flufend i-AI H5N9 H7N1 Merial Italia SpaMerialA/chicken/Italy/1067/99 (H7N1) and A/chicken/Italy/22A/98 (H5N9)H7N9 and H5N9 inactivated, oil H7N1 and H5N9 Qingdao Yebio Bioengineering Co. Ltd Qingdao City, Shandong province, ChinaNational Animal Quarantine Institute of the Ministry of AgricultureNo info availableH5N2 LP and H9 inactivated, oil adjuvant, vAccine Production Centre, Karachi, PakistanMinistry of Food, Agriculture and Livestock, Province of Sindh, PakistanH7N3 and H9N2 vaccineInactivated Avicina Laboratories, Lahore, PakistanH7N3 and H9N2 InactivatedBiolab (pvt)

7 Ltd, Rawalpindi, Pakistan H7N3 and H9N2 InactivatedOtoman Pharma , Lahore, PakistanH7N3 and H9N2 InactivatedMonovAlent inActivAted H7 vAccinesBiomune vaccines, USACeva Sant Animale SAA/Chicken/New York/273874/03 H7N2 Inactivated, oil adjuvantLayermune AIV H7N2 Biomune vaccines, USACeva Sant Animale SAA/Turkey/Utah/24721-10/95 H7N3 Inactivated, oil adjuvantLayermune AIV H7N3 Lohmann Animal HealthH7N3 Inactivated, oil , Netherlands/SpainIntervetA/Chicken/Italy /473/99 H7N1 Inactivated, oil influenzA H7N1 IntervetA/duck/Potsdam/15/80 H7N7 Inactivated, oil Nobilis influenzA H7N7 Merial Italia SpaMerialH7N1 FLU (for use in Italy)MerialH7N1 or H7N3 Sindh vAccine Production Centre, Karachi, PakistanMinistry of Food, Agriculture and Livestock, Province of Sindh, PakistanH7N3 Inactivated laboratoryAffiliation strainsubtypevaccine categoryWeb sitecommercial nameAviAn influenzA vAccine producers And suppliers for poultry FAO/EMPRES February 2009 Page 4 Avicina Laboratories, Lahore, PakistanH7N3 InactivatedBiolab (pvt)

8 Ltd, Rawalpindi, Pakistan H7N3 InactivatedOtoman Pharma , Lahore, PakistanH7N3 InactivatedFort Dodge Animal Health, Overland Park, USAFort Dodge Animal Health, Overland Park, USAA/CK/NewYork/273874/2003H7N2oil adjuvantAvian influenzA vAccine , H7N2 SubtypeFort Dodge Animal Health, Overland Park, USAFort Dodge Animal Health, Overland Park, USAA/TY/Oregon/1971H7N3oil adjuvantAvian influenzA vAccine , H7N3 SubtypeFort Dodge Animal Health, Overland Park, USAFort Dodge Animal Health, Overland Park, USAA/CK/Italy/1067/H7N1/1999H7N1 Oil adjuvantPOULVAC Flufend i-AI H7N1 MonovAlent inActivAted H9 vAccinesMerialH9N2 Inactivated, oil H9 Sindh vAccine Production Centre, Karachi, PakistanMinistry of Food, Agriculture and Livestock, Province of Sindh, PakistanH9N2 Inactivated Avicina Laboratories, Lahore, PakistanH9N2 InactivatedBiolab (pvt) Ltd, Rawalpindi, Pakistan H9N2 InactivatedOtoman Pharma , Lahore, PakistanH9N2 InactivatedRazi vAccine and Serum Research Institute, IranH9N2 Inactivated, oil Biological Laboratories TEVA Ltd.

9 , IsraelH9N2 Inactivated, oil , IsraelH9N2 Inactivated, oil Biological Laboratories Ltd, IsraelH9N2 Inactivated, oil , oil influenzA H9N2 JovacJordan Bio-Industries Center, JordanH9N2 Inactivated, oil adjuvantUnder constructionJovazeit 7