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1 No Mouse Microbiologic Test Reports [Monthly report:December] No21-004 IBF +/+ Leprdb/JclKK-Ay/TaJclBALB/cAJcl-nu/nuC3 +/m+JclKK/TaJclBALB/cAJcl-nu/+129+Ter/Sv Jcl + Leprdb/+ Leprdb/JclC57BL/6 NJclBALB/cByJJclDBA/2JJ CultivationDermatophytes 0/100/100/100/5 Citrobacter rodentium 0/100/100/100/5 Pasteurella pneumotropica 0/100/100/100/5 Corynebacterium kutscheri 0/100/100/100/5 Pseudomonas aeruginosa 0/100/100/100/5 Salmonella spp. 0/100/100/100/5 Staphylococcus aureus 0/5 Mycoplasma pulmonis 0/100/100/100/5 SerologyCorynebacterium kutscheri 0/100/100/100/5 Salmonella typhimurium 0/100/100/100/5 Clostridium piliforme 0/100/100/100/5 Mycoplasma pulmonis 0/100/100/100/5 Mouse hepatitis virus 0/100/100/100/5 Sendai virus 0/100/100/100/5 Ectromelia virus 0/100/100/100/5 Mouse adenovirus (FL) 0/100/100/100/5 Lymphocytic c.

2 Virus Hantavirus MicroscopyIntestinal protozoa 0/100/100/100/5 Ectoparasites 0/100/100/100/5 Pinworm 0/100/100/100/5 PCRP neumocystis murina Helicobacter hepaticus Helicobacter bilis SerologyEDIM virus(Rotavirus) Pneumonia virus of mice Minute virus of mice Mouse cytomegalovirus Mouse encephalomyelitis virus Reovirus type3 Filobacterium rodentium(CAR bacillus) (Frequency of Tests) 1 * Use sentinel animals for the test for 1 strain/room /Every month, 2 /Twice a year, 2 ( )/Twice a year (Immunodeficient model only), 1 /Once a year, 4 /4 times a year, ( )/Every month (Immunodeficient model only) (MBF) (FTSC) (FBF) (IBF) No Mouse Microbiologic Test Reports [Monthly report:December] No21-004 IBF No5 IBF 0/100/100/100/10 Citrobacter rodentium 0/100/100/100/10 Pasteurella pneumotropica 0/100/100/100/10 Corynebacterium kutscheri 0/100/100/100/10 Pseudomonas aeruginosa 0/100/100/100/10 Salmonella spp.

3 0/100/100/100/10 Staphylococcus aureus Mycoplasma pulmonis 0/100/100/100/10 SerologyCorynebacterium kutscheri 0/100/100/100/10 Salmonella typhimurium 0/100/100/100/10 Clostridium piliforme 0/100/100/100/10 Mycoplasma pulmonis 0/100/100/100/10 Mouse hepatitis virus 0/100/100/100/10 Sendai virus 0/100/100/100/10 Ectromelia virus 0/100/100/100/10 Mouse adenovirus (FL) 0/100/100/100/10 Lymphocytic c. virus Hantavirus MicroscopyIntestinal protozoa 0/100/100/100/10 Ectoparasites 0/100/100/100/10 Pinworm 0/100/100/100/10 PCRP neumocystis murina Helicobacter hepaticus Helicobacter bilis SerologyEDIM virus(Rotavirus) Pneumonia virus of mice Minute virus of mice Mouse cytomegalovirus Mouse encephalomyelitis virus Reovirus type3 Filobacterium rodentium(CAR bacillus) (Frequency of Tests) 1 * Use sentinel animals for the test for 1 strain/room /Every month, 2 /Twice a year, 2 ( )/Twice a year (Immunodeficient model only), 1 /Once a year, 4 /4 times a year, ( )/Every month (Immunodeficient model only) (MBF) (FTSC)

4 (FBF) (IBF) No Mouse Microbiologic Test Reports [Monthly report:December] No21-004 FBF :ICRBALB/cAJclC3H/HeN JclSKG/JclC57BL/6 NJclNOD/ShiJclB6D2F1/JclB6C3F1/JclCultiv ationDermatophytes Citrobacter rodentium 0/100/100/100/10 Pasteurella pneumotropica 0/100/100/100/10 Corynebacterium kutscheri 0/100/100/100/10 Pseudomonas aeruginosa 0/100/100/100/10 Salmonella spp. 0/100/100/100/10 Staphylococcus aureus Mycoplasma pulmonis 0/100/100/100/10 SerologyCorynebacterium kutscheri 0/100/100/100/10 Salmonella typhimurium 0/100/100/100/10 Clostridium piliforme 0/100/100/100/10 Mycoplasma pulmonis 0/100/100/100/10 Mouse hepatitis virus 0/100/100/100/10 Sendai virus 0/100/100/100/10 Ectromelia virus 0/100/100/100/10 Mouse adenovirus (FL) 0/100/100/100/10 Lymphocytic c.

5 Virus Hantavirus MicroscopyIntestinal protozoa 0/100/100/100/10 Ectoparasites 0/100/100/100/10 Pinworm 0/100/100/100/10 PCRP neumocystis murina Helicobacter hepaticus Helicobacter bilis SerologyEDIM virus(Rotavirus) Pneumonia virus of mice Minute virus of mice Mouse cytomegalovirus Mouse encephalomyelitis virus Reovirus type3 Filobacterium rodentium(CAR bacillus) (Frequency of Tests) 1 * Use sentinel animals for the test for 1 strain/room /Every month, 2 /Twice a year, 2 ( )/Twice a year (Immunodeficient model only), 1 /Once a year, 4 /4 times a year, ( )/Every month (Immunodeficient model only) (MBF) (FTSC) (FBF) (IBF) No Mouse Microbiologic Test Reports [Monthly report:December] No21-004 FBF No3 FBF BS1 FTSC BS6 CByB6F1-Tg(HRAS)2 Jic (tg/wt)MCH(ICR)/JclCByB6F1-Tg(HRAS)2 Jic (tg/wt)CByB6F1-Tg(HRAS)2 Jic (tg/wt)CByB6F1-Tg(HRAS)2 Jic (wt/wt)FVB/NJ CByB6F1-Tg(HRAS)2 Jic (wt/wt)CByB6F1-Tg(HRAS)2 Jic (wt/wt)C57BL/10-mdx/JclCultivationDermat ophytes Citrobacter rodentium 0/100/100/100/10 Pasteurella pneumotropica 0/100/100/100/10 Corynebacterium kutscheri 0/100/100/100/10 Pseudomonas aeruginosa 0/100/100/100/10 Salmonella spp.

6 0/100/100/100/10 Staphylococcus aureus Mycoplasma pulmonis 0/100/100/100/10 SerologyCorynebacterium kutscheri 0/100/100/100/10 Salmonella typhimurium 0/100/100/100/10 Clostridium piliforme 0/100/100/100/10 Mycoplasma pulmonis 0/100/100/100/10 Mouse hepatitis virus 0/100/100/100/10 Sendai virus 0/100/100/100/10 Ectromelia virus 0/100/100/100/10 Mouse adenovirus (FL) 0/100/100/100/10 Lymphocytic c. virus Hantavirus MicroscopyIntestinal protozoa 0/100/100/100/10 Ectoparasites 0/100/100/100/10 Pinworm 0/100/100/100/10 PCRP neumocystis murina Helicobacter hepaticus Helicobacter bilis SerologyEDIM virus(Rotavirus) Pneumonia virus of mice Minute virus of mice Mouse cytomegalovirus Mouse encephalomyelitis virus Reovirus type3 Filobacterium rodentium(CAR bacillus) (Frequency of Tests) 1 * Use sentinel animals for the test for 1 strain/room /Every month, 2 /Twice a year, 2 ( )/Twice a year (Immunodeficient model only), 1 /Once a year, 4 /4 times a year, ( )/Every month (Immunodeficient model only) (MBF) (FTSC)

7 (FBF) (IBF) No Mouse Microbiologic Test Reports [Monthly report:December] No21-004 MBF No2 FBF +BALB/cAJcl-nu/+ +/+JclCultivationDermatophytes Citrobacter rodentium 0/50/50/50/5 Pasteurella pneumotropica 0/50/50/50/5 Corynebacterium kutscheri 0/50/50/50/5 Pseudomonas aeruginosa 0/50/50/50/5 Salmonella spp. 0/50/50/50/5 Staphylococcus aureus 0/50/50/50/5 Mycoplasma pulmonis 0/50/50/50/5 SerologyCorynebacterium kutscheri 0/50/50/50/5 Salmonella typhimurium 0/50/50/50/5 Clostridium piliforme 0/50/50/50/5 Mycoplasma pulmonis 0/50/50/50/5 Mouse hepatitis virus 0/50/50/50/5 Sendai virus 0/50/50/50/5 Ectromelia virus 0/50/50/50/5 Mouse adenovirus (FL) 0/50/50/50/5 Lymphocytic c.

8 Virus Hantavirus MicroscopyIntestinal protozoa 0/50/50/50/5 Ectoparasites 0/50/50/50/5 Pinworm 0/50/50/50/5 PCRP neumocystis murina Helicobacter hepaticus Helicobacter bilis SerologyEDIM virus(Rotavirus) Pneumonia virus of mice Minute virus of mice Mouse cytomegalovirus Mouse encephalomyelitis virus Reovirus type3 Filobacterium rodentium(CAR bacillus) (Frequency of Tests) 1 * Use sentinel animals for the test for 1 strain/room /Every month, 2 /Twice a year, 2 ( )/Twice a year (Immunodeficient model only), 1 /Once a year, 4 /4 times a year, ( )/Every month (Immunodeficient model only) (MBF) (FTSC) (FBF) (IBF) No Rat Microbiologic Test Reports [Monthly report:December] No21-005 IBF :SDF344/NJcl-rnu/rnuJcl:WistarF344/NJcl- rnu/+ODS/ShiJcl-+/+ODS/ShiJcl-od/odSDT/J clF344/JclCultivationDermatophytes 0/10 Pasteurella pneumotropica 0/100/50/10 Bordetella bronchiseptica 0/100/50/10 Corynebacterium kutscheri 0/100/50/10 Pseudomonas aeruginosa 0/100/50/10 Salmonella spp.

9 0/100/50/10 Staphylococcus aureus 0/5 Mycoplasma pulmonis 0/100/50/10 Streptococcus pneumoniae 0/100/50/10 SerologyCorynebacterium kutscheri 0/100/50/10 Salmonella typhimurium 0/100/50/10 Clostridium piliforme 0/100/50/10 Mycoplasma pulmonis 0/100/50/10 Sialodacryoadenitis virus 0/100/50/10 Sendai virus 0/100/50/10 Mouse adenovirus (FL) 0/100/50/10 Hantavirus Lymphocytic c. virus MicroscopyEctoparasites 0/100/50/10 Intestinal protozoa 0/100/50/10 Pinworm 0/100/50/10 PCRP neumocystis carinii Helicobacter hepaticus Helicobacter bilis SerologyPneumonia virus of mice Minute virus of mice Mouse encephalomyelitis virus Reovirus type3 Filobacterium rodentium(CAR bacillus) H-1 virus Kilham rat virus (Frequency of Tests) 1 * Use sentinel animals for the test for 1 strain/room /Every month, 2 /Twice a year, 2 ( )/Twice a year (Immunodeficient model only), 1 /Once a year, 4 /4 times a year, ( )/Every month (Immunodeficient model only) (MBF) (FTSC)

10 (FBF) (IBF) No Rat Microbiologic Test Reports [Monthly report:December] No21-005 FBF No1 SDT fatty/Jcl BrlHan:WIST@Jcl(GALAS)RCS/Jcl- / RCS/Jcl-+/+CultivationDermatophytes Pasteurella pneumotropica 0/100/10 Bordetella bronchiseptica 0/100/10 Corynebacterium kutscheri 0/100/10 Pseudomonas aeruginosa 0/100/10 Salmonella spp. 0/100/10 Staphylococcus aureus Mycoplasma pulmonis 0/100/10 Streptococcus pneumoniae 0/100/10 SerologyCorynebacterium kutscheri 0/100/10 Salmonella typhimurium 0/100/10 Clostridium piliforme 0/100/10 Mycoplasma pulmonis 0/100/10 Sialodacryoadenitis virus 0/100/10 Sendai virus 0/100/10 Mouse adenovirus (FL) 0/100/10 Hantavirus Lymphocytic c.