Transcription of Connective Tissue Disease Cascade (CTDC)
1 03/2015 mayo Foundation for medical Education and Research (MFMER). All rights reserved. mayo , mayo medical laboratories and the triple-shield mayo logo are trademarks and/or service marks of Tissue Disease Cascade ( ctdc ) 20 U<20 UCTDC / Connective Tissue Diseases Cascade , SerumNo further testingCyclic Citrullinated Peptide Antibodies, IgG, SerumPositive result supports the diagnosis of RAAntibody to Extractable Nuclear Antigen Evaluation, SerumThis test includes the following IgGantibodies, which are automaticallyperformed: SS-A/Ro SS-B/La Sm RNP Scl 70 Jo 1 DNA Double-Stranded (dsDNA) Antibodies with Reflex, IgG, SerumCRITH / DNA Double-Stranded(dsDNA)
2 Antibodies by Crithidialuciliae IFA, IgG, Serum U U U U U USm AntibodiesPositive result supportsdiagnosis of LESS-A/Ro AntibodiesPositive result supports the diagnosis of Sj gren syndrome or other CTDP ositive result supportsthe diagnosis of LENegative resultUnable to confirm borderline positive result obtained by EIAScl 70 AntibodiesPositive result supportsdiagnosis of sclerodermaRNP AntibodiesPositive result supports diagnosis of mixed Connective Tissue diseaseSS-B/La AntibodiesPositive result supports diagnosis of Sj gren syndrome or other CTDJo 1 AntibodiesPositive result
3 Supportsdiagnosis of polymyositisPositive result supports the diagnosis of LEPositive result supports the diagnosis of CREST syndromePositive result supports the diagnosis of LE and may indicate the presence of CNS involvementCentromere Antibodies, IgG, SerumRibosome P Antibodies, IgG, SerumNo further testingAntinuclear Antibodies(ANA), Serum U U U30-75 IU/mL>75 IU/mL< UCNS=central nervous systemCREST=calcinosis, Raynaud Disease , esophageal motility disorder, sclerodactyly, and Tissue diseaseSLE=systemic lupus erythematosusNOTE: Positive results not diagnostic for any CTD and should be interpreted within the clinical context of the patient.
