Transcription of 女性のからだと卵子の老化 ... - kenko-kenbi.or.jp
1 10 15 20 25 30 35 40 45 50 55.. 10 15 20 25 30 35 40 45 50 55.. (2000) .. 25 38 . 0 7 14 21 28.. 3 7 .. Output . - - .. GnRH ( ).. negative feedback FSH ( ). LH ( ).. E2 ( ). P4 ( ).. 15% 10% .. 100. 90.. 80.. 70. 60. 50. 40.. 30. 20. 10. 0. 10 12 14 16 18 20 22 24.. (2004) . BMI . BMI 21 . BMI 16 . 80 . BMI BMI 25 . 75. BMI=23. 70.. 65 BMI=21 . 60. 55. BMI< .. 50 BMI=18 . 45. BMI=16 . 40.. 35. 30. 145 150 155 160 165 170 175. (cm) BMI (kg) (m)2.. 13-14 20 . 20 . 10.. 8.. 6.. 4.. 2. 0. 1. 2. 3. 4. 5. 6. 7. 8. 0. 10. -1. -1. -1. -1. -1. -1. -1. -1. -2. 9- 10. 11. 12. 13. 14. 15. 16. 17. 18.. (2004) .. 120. 100.. 80. 60.. 40.. 20. 0.. (1998) .. 60. 50 . 40. 30 . 20. 10 . 0. ( , , 2004).. (WHO Global Database on Body Mass Index (BMI) 2011-1-24).. Barker . DOHaD . Developmental Origins of Health and Disease .. ( ).. 3400.. 3300 3230g 3200. 3150g 3160g 3100. 3050g 3060g 3000. 2900 2960g 1980 1990 2000 ( ). ( ).. 20 20 24 25 29 30 34 35 ( , 2006).
2 !? .. 2006,9,19 .. 15 20 20. 2000 5 . 2000 6 21 .. No!! .. My Body & Cycle . OC OC .. (PMS) .. 43.. 17.. 3.. 0 20 40 60 %. OC OC 2003 .. (Guillebaud, 1998). CQ408 . Answer 1. B . 2.. B . 3. C . 2014). CQ409 . Answer 1. Holmstrom Kaufmann . C . 2. C . 3. 70 .. B . 4.. NSAIDs OC) B . 2014).. PICK UP.. 26 16 16 16 . 1 2.. PLoS ONE 2010 .. 5 6 . 6 .. Asada Ladies Clinic .. 70 80 .. 20 20 . 30 30 .. Fecund Sterile . ( .. 0. 15 20 22 25 30 35 40 45 50.. 22 . O Connor et al,1998 .. 70 . 60 . 50. 40. 30. 20. 10. 0. 20-24 25-29 30-34 35-39 40-44. Menken J et al, Science ,1986.. 28. 10 . Percentage of cases 24. 20.. 16 . 12. 8.. 4. 0. 17 23 29 35 41 47 53 59 65. Female Age (yrs). BALSAC demographic database (BALSAC project at the University of Quebec in Chicoutimi (n = 1040)). Prospect-EPIC (European Prospective Investigation into Cancer and Nutrition) study (n = 3483).. 2012.. 2012.. T . ( . 4000 1 .. 3500. 40 370 . 3000 45 3780 . 47 2 3 . 2500. (1 30.
3 2000. 1500. 1000. 500. 0. 20 25 30 5 40 45.. ( ).. 40 . 35 39 40 . 20 34 .. 21 .. 28 .. 20 .. 25 29 .. 18 22 . 16. 14. 12. 10. 8. 6. 4. 2. 0.. 22 .. 20 . ( . 14-23 10 . 60. 50. 40. 30. 20. 10 0. (.))
