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Kidney - Introduction - National Toxicology Program
Kidney – Introduction The kidneys are one of the more important tissues examined. Because of its role in the filtration, metabolism, and excretion of compounds, it is often the site of test-article-induced lesions. In addition, a wide range of spontaneous renal lesions may be observed. Chronic progressive nephropathy (CPN), a
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Lung - Emphysema
ntp.niehs.nih.govLung – Emphysema Recommendation: Lung - Emphysema should be diagnosed and assigned aseverity grade. Associated lesions, such as inflammation, should be diagnosed separately. If the lesion is considered to be an artifact, emphysema should not be diagnosed, but a tissue note may be entered to that effect.
Skeletal Muscle - Regeneration
ntp.niehs.nih.govSkeletal Muscle – Regeneration Figure Legend: Figure 1 Skeletal muscle - Regeneration in a male Harlan Sprague-Dawley rat from a subchronic study. Myoblasts and cytoplasmic basophilia (arrows) characterize regeneration of a previously damaged muscle fiber.
Kidney, Renal Tubule – Regeneration
ntp.niehs.nih.govKidney, Renal Tubule – Regeneration Figure Legend: Figure 1 Kidney, Renal tubule - Regeneration in a male rat from an acute study. Regeneration following acute tubule epithelial injury is characterized by flattened epithelium and tubule epithelial cell …
Public Health Goal for Chromium In Drinking Water
ntp.niehs.nih.govThis Public Health Goal (PHG) technical support document provides information on health effects from contaminants in drinking water. PHGs are developed for chemical contaminants based on the best
Test Method Protocol for Solubility Determination (2003)
ntp.niehs.nih.govTest Method Protocol for Solubility Determination Phase III - Validation Study September 24, 2003 7.5 mg/mL Bovine Pituitary Extract (BPE) 2.0 mL . Clonetics Calcium SingleQuots“ are 2 mL of 300 mM calcium. 165 ml of solution per 500 mL calcium-free medium equals 0.10 mM calcium in the .
DRAFT PROTOCOL FOR SYSTEMATIC REVIEW TO EVALUATE …
ntp.niehs.nih.govdraft protocol for systematic review to evaluate the evidence for an association between bisphenol a (bpa) exposure and obesity . april 9, 2013
The National Program Synthetic Turf/Recycled Tire Crumb ...
ntp.niehs.nih.gov•Crumb rubber (CR) manufactured by shredding recycled automotive tires into rubber particles has been employed as the infill material in synthetic turf fields. •CR is suspected to contain potential carcinogenic and toxic substances.
Synthetic Turf/Recycled Tire Crumb Rubber Research …
ntp.niehs.nih.govMay 2017 2 risk. This is the focus of NTP’s studies. Information gained from these studies will inform OEHHA’s evaluation of health impacts associated with the use of crumb rubber in synthetic turf
RoC Profile: Asbestos; 14th RoC 2016 - ntp.niehs.nih.gov
ntp.niehs.nih.govBy 2008, chrysotile was the only type of asbestos used in the United States (Virta 2008); 64% of chrysotile used was categorized as grade 7 asbestos (with fiber lengths less than 3 mm), followed by grades 4, 5, and 3 (Virta 2002a, 2009).
Thyroid Gland, Follicle - Pigment
ntp.niehs.nih.govThyroid Gland, Follicle – Pigment pigmentation can be seen as a background change in both control and treated rats (Figure 3 and Figure 4). Recommendation: Definitive pigment identification is often difficult in histological sections, even with a battery of special stains.
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