Safety Data Sheet - drp8p5tqcb2p5.cloudfront.net

1 Safety data Sheet silver nitrate Solution # 220 Page 1 of 8 Issue Date: 24 October, 2011 Rev A SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND THE COMPANY Product Identifier Trade Name silver nitrate Solution msds #: 220 msds Date October 25, 2011 Relevant Identified Uses of the Substance or Mixture and Uses Advised Against Product Use: Use with the Modified Grocott s Methenamine silver Stain Uses Advised Against: All other uses.

2 Details of the Supplier of the Substance or Mixture Manufacturer/Preparer: Leica Biosystems Richmond, Inc. 5205 Route 12 Richmond, IL 60071 800-225-8867 Leica Microsystems Canada, Inc. 83 Terracon Place Winnipeg, Manitoba R2J 4B3 800-665-7425 Emergency Telephone Number Emergency Spill Information 1-800- 424-9300 (CHEMTREC) +1-703-527-3887 International calls (call collect) Other Product Information: 1-800-225-8867 SECTION 2: HAZARDS IDENTIFICATION Classification of the Substance or Mixture CLP/GHS Classification (1272/2008): Physical: Health.

3 Environmental Not Hazardous Not Hazardous Aquatic Acute Toxicity Category 1 Aquatic Chronic Toxicity Category 1 EU Classification (67/548/EEC): Not classified as dangerous Label Elements: WARNING! Contains silver nitrate . #220 Page 2 of 8 Issue Date: 24 October, 2011 Rev A Hazard Phrases H410 Very toxic to aquatic life with long lasting effects.

4 Precautionary Phrases P273 Avoid release to the environment P391 Collect spillage P501 Dispose of container / contents to approved disposal site in accordance with all local and national regulations. Other Hazards: None SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS Substances Chemical Name CAS Number / EINECS Number / REACH Reg. Number % (w/w) EU Classification (67/548/EEC) CLP/GHS Classification (1272/2008) silver nitrate 7761-88-8 231-853-9 < O, C, N, R8, R34, R50/53 Oxidizing Solid Category 2 (H272) Skin Corrosive Category 1B (H314) Aquatic Acute Toxicity Category 1 (H400) Aquatic Chronic Toxicity Category 1 (H410) See Section 16 for full text of GHS and EU Classifications.

5 SECTION 4: FIRST AID MEASURES Description of First Aid Measures First Aid Eye contact: Flush eyes with water while lifting the upper and lower lids. Get medical attention if irritation persists Skin contact: Wash with soap and water. Get medical attention if irritation develops. Remove contaminated clothing and launder before reuse. Inhalation: Remove victim to fresh air. Get medical attention if irritation persists. Ingestion: If small quantities are swallowed, rinse out mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious or drowsy person.

6 If large amounts are swallowed or if irritation or discomfort occurs, get medical attention. See Section 11 for more detailed information on health effects. Most Important symptoms and effects, both acute and delayed: May cause mild eye and skin irritation. Indication of any immediate medical attention and special treatment needed: Immediate medical treatment is not required. #220 Page 3 of 8 Issue Date: 24 October, 2011 Rev A SECTION 5: FIREFIGHTING MEASURES Extinguishing Media: Use any media that is suitable for the surrounding fire.

7 Special Hazards Arising from the Substance or Mixture Unusual Fire and Explosion Hazards: silver nitrate is an oxidizer: High concentration in contact with combustible materials may cause fire. Aqueous solution should not present a fire hazard. Combustion Products: Oxides of nitrogen. Advice for Fire-Fighters: Self-contained breathing apparatus and protective clothing should be worn in fighting large fires involving chemicals. Determine the need to evacuate or isolate the area according to your local emergency plan. SECTION 6: ACCIDENTAL RELEASE MEASURES Personal Precautions, Protective Equipment and Emergency Procedures: Wear appropriate protective equipment.

8 Environmental Precautions: Prevent entry in storm sewers and waterways. Report spill as required by local and federal regulations. Methods and Material for Containment and Cleaning Up: Stop spill at the source if it is safe to do so. Absorb with an inert material. Collect into a suitable container for disposal. Reference to Other Sections: Refer to Section 8 for personal protective equipment and Section 13 for disposal information. SECTION 7: HANDLING and STORAGE Precautions for Safe Handling: Avoid eye and skin contact. Avoid breathing mists. Use with adequate ventilation.

9 Wash thoroughly after handling. Remove contaminated clothing and launder before re-use. Keep containers closed when not in use. Conditions for Safe Storage, Including any Incompatibilities: Protect containers from physical damage. Store in a cool area. Keep away from excessive heat. Keep containers closed when not in use. Empty containers retain product residues. Do not cut, weld, braze, etc. on or near empty containers. Follow all msds precautions in handling empty containers Specific end use(s): Industrial uses: None identified Professional uses: Use with the Modified Grocott s Methenamine silver Stain #220 Page 4 of 8 Issue Date: 24 October, 2011 Rev A SECTION 8.

10 EXPOSURE CONTROLS/PERSONAL PROTECTION Control Parameters: Chemical Name US OEL EU IOEL UK OEL Germany OEL silver nitrate mg/m3 TWA OSHA PEL (as silver ) mg/m3 TWA ACGIH TLV (as silver ) None Established mg/m3 TWA mg/m3 TWA (Inhalable) Refer to local or national authority for exposure limits not listed above. Chemical Name Biological Limit Value silver nitrate None Established Exposure Controls: Recommended Monitoring Procedures: Collection on filters with analysis by AA / Appropriate Engineering Controls: Use with adequate local exhaust ventilation to maintain exposure levels below the occupational exposure limits.