SAFETY DATA SHEET - zoetisUS.com

1 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND THECOMPANY/UNDERTAKINGP roduct IdentifierMaterial Name: ChlorMax 50 Trade Name:Not establishedChemical Family:Tetracycline derivativeRelevant Identified Uses of the Substance or Mixture and Uses Advised AgainstIntended Use:Veterinary product , Feed additiveDetails of the Supplier of the SAFETY Data Sheet2. HAZARDS IDENTIFICATIONA ppearance:Brown granular materialClassification of the Substance or MixtureGHS - ClassificationReproductive Toxicity: Category 1 AUS OSHA Specific - ClassificationPhysical Hazard: Combustible DustEU Classification:EU Indication of danger: Toxic to reproduction: Category 1EU Symbol:TR61 - May cause harm to the unborn ElementsSignal Word:DangerHazard Statements:H360 - May damage fertility or the unborn childMay form combustible dust concentrations in airPrecautionary Statements:P201 - Obtain special instructions before useP202 - Do not handle until all SAFETY precautions have been read and understoodP210 - Keep away from heat/sparks/open flames/hot surfaces.

2 - No smokingP280 - Wear protective gloves/protective clothing/eye protection/face protectionP308 + P313 - IF exposed or concerned: Get medical attention/adviceP405 - Store locked upP501 - Dispose of contents/container in accordance with all local and national regulations_____700101 Page 1 of 7 Zoetis Campus Drive, Box 651 Florham Park, New Jersey 07932 (USA)Rocky Mountain Poison Control Center Phone: 1-866-531-8896 product Support/Technical Services Phone: 1-800-366-5288 Zoetis Belgium 201930 ZaventemBelgiumRevision date: 09-Mar-2014 Emergency telephone number:CHEMTREC (24 hours): 1-800-424-9300 SAFETY DATA SHEETE mergency telephone number:International CHEMTREC (24 hours): +1-703-527-3887 Version: SAFETY DATA SHEET_____Other HazardsShort Term:Dust may cause transient irritation . May be harmful if Term:Animal studies have shown a potential to cause adverse effects on the Hazard Classification(NOHSC):Hazardous Substance.

3 Non-Dangerous :This document has been prepared in accordance with standards for workplace SAFETY , whichrequires the inclusion of all known hazards of the product or its ingredients regardless of thepotential risk. The precautionary statements and warning included may not apply in all needs may vary depending upon the potential for exposure in your COMPOSITION/INFORMATION ON INGREDIENTSH azardousIngredientCAS NumberEUEINECS/ELINCSListEU ClassificationGHSC lassification%Chlortetracycline57-62-520 0-341-7 Repr. ;R61 Repro. Tox. Cat. 1A(H360)11 IngredientCAS NumberEUEINECS/ELINCSListEU ClassificationGHSC lassification%Roughage and mineral carrierMixtureNot ListedNot ListedNot Listed89 Additional Information:Ingredient(s) indicated as hazardous have been assessed under standards for the full text of the R phrases and CLP/GHS abbreviations mentioned in this Section, see Section 164. FIRST AID MEASURESD escription of First Aid MeasuresEye Contact:Flush eye(s) immediately with plenty of water.

4 If irritation occurs or persists, get Contact:If irritation occurs, wash exposed area with soap and water, remove contaminated clothing andobtain medical :Never give anything by mouth to an unconscious person. Wash out mouth with water. Do notinduce vomiting unless directed by medical personnel. Seek medical attention :Remove to fresh air and keep patient at rest. Seek medical attention Important Symptoms and Effects, Both Acute and Delayed_____700101 Revision date: 09-Mar-2014 Material Name: ChlorMax 50 Version: 2 of 7 SAFETY DATA SHEET_____Symptoms and Effects ofExposure:For information on potential signs and symptoms of exposure, See Section 2 - HazardsIdentification and/or Section 11 - Toxicological ConditionsAggravated by Exposure:None knownIndication of the Immediate Medical Attention and Special Treatment NeededNotes to Physician:None5. FIRE-FIGHTING MEASURESE xtinguishing Media:Extinguish fires with CO2, extinguishing powder, foam, or Hazards Arising from the Substance or MixtureHazardous CombustionProducts:Formation of toxic gases is possible during heating or / Explosion Hazards:Dust can form an explosive mixture in air.

5 Fine particles (such as dust and mists) may for Fire-FightersDuring all fire fighting activities, wear appropriate protective equipment, including self-contained breathing ACCIDENTAL RELEASE MEASURESP ersonal Precautions, Protective Equipment and Emergency ProceduresAvoid dust formation. Personnel involved in clean-up should wear appropriate personal protective equipment (see Section 8).Minimize PrecautionsPlace waste in an appropriately labeled, sealed container for disposal. Care should be taken to avoid environmental and Material for Containment and Cleaning UpMeasures for Cleaning /Collecting:Eliminate possible ignition sources ( , heat, sparks, flame, impact, friction, electricity), andfollow appropriate grounding procedures. Contain the source of the spill if it is safe to do spilled material by a method that controls dust generation. Place waste in anappropriate container for Consideration forLarge Spills:Non-essential personnel should be evacuated from affected area.

6 Report emergencysituations immediately. Clean up operations should only be undertaken by trained HANDLING AND STORAGEP recautions for Safe HandlingEliminate possible ignition sources ( , heat, sparks, flame, impact, friction, electricity), and follow appropriate grounding andbonding procedures. Avoid contact with eyes, skin and clothing. Avoid breathing dust. Minimize dust generation andaccumulation. Use with adequate ventilation. When handling, use appropriate personal protective equipment (see Section 8).Wash thoroughly after handling. Releases to the environment should be avoided. Review and implement appropriate technicaland procedural waste water and waste disposal measures to prevent occupational exposure or environmental points of process emissions of this material to the atmosphere should be controlled with dust collectors, HEPA filtrationsystems or other equivalent for Safe Storage, Including any IncompatibilitiesStorage Conditions:Store as directed by product packaging.

7 Keep away from heat, sparks, flame, and othersources of Materials:Strong acids and strong bases Strong oxidising end use(s):No data available_____700101 Page 3 of 7 Revision date: 09-Mar-2014 Material Name: ChlorMax 50 Version: SAFETY DATA SHEET_____8. EXPOSURE CONTROLS / PERSONAL PROTECTIONC ontrol ParametersRefer to available public information for specific member state Occupational Exposure ControlsEngineering Controls:Engineering controls should be used as the primary means to control exposures. Keepairborne contamination levels below the exposure limits listed above in this section. Generalroom ventilation is adequate unless the process generates dust, mist or ProtectiveEquipment:Refer to applicable national standards and regulations in the selection and use of personalprotective equipment (PPE).Hands:Impervious gloves are recommended if skin contact with drug product is possible and for bulkprocessing :Wear SAFETY glasses or goggles if eye contact is :Impervious protective clothing is recommended if skin contact with drug product is possible andfor bulk processing protection:If the applicable Occupational Exposure Limit (OEL) is exceeded, wear an appropriaterespirator with a protection factor sufficient to control exposures to below the PHYSICAL AND CHEMICAL PROPERTIESS olvent Solubility:No data availableWater Solubility:No data availablepH:No data Point ( C):No data availableBoiling Point ( C):No data Coefficient: (Method, pH, Endpoint, Value)No data availableDecomposition Temperature ( C):No data Rate (Gram/s):No data availableVapor Pressure (kPa):No data availableVapor Density (g/ml):No data availableRelative Density:No data availableViscosity.

8 No data availableFlammablity:Autoignition Temperature (Solid) ( C):No data availableFlammability (Solids):No data availableFlash Point (Liquid) ( C):No data availableUpper Explosive Limits (Liquid) (% by Vol.):No data availableLower Explosive Limits (Liquid) (% by Vol.):No data available_____700101 Zoetis OEL TWA mg/m Revision date: 09-Mar-2014 Latvia OEL - mg/m3 Material Name: ChlorMax 50 Physical State:Granular materialColor:BrownVersion: :SlightChlortetracyclineOdor Threshold:No data 4 of 7 Molecular Formula:MixtureMolecular Weight:Mixture SAFETY DATA SHEET_____10. STABILITY AND REACTIVITYR eactivity:No data availableChemical Stability:Stable under normal conditions of of Hazardous ReactionsOxidizing Properties:NoneConditions to Avoid:Keep away from heat, spark, flames and all other sources of ignition. Avoid dispersion as adust Materials:Strong acids and strong bases Strong oxidising DecompositionProducts:Thermal decomposition products may include carbon monoxide, carbon dioxide, oxides ofnitrogen and hydrogen TOXICOLOGICAL INFORMATIONI nformation on Toxicological EffectsGeneral Information:The information included in this section describes the potential hazards of the activeingredient(s).

9 Acute Toxicity: (Species, Route, End Point, Dose)Repeated Dose Toxicity: (Duration, Species, Route, Dose, End Point, Target Organ)Reproduction & Development Toxicity: (Duration, Species, Route, Dose, End Point, Effect(s))Reproductive EffectsAnimal studies revealed that tetracyclines cross the placenta, are found in fetal tissues, andcan have toxic effects on the developing fetus. Tetracyclines as a class are capable ofcrossing the placenta and causing staining of the primary Toxicity: (Study Type, Cell Type/Organism, Result)Carcinogenicity: (Duration, Species, Route, Dose, End Point, Effect(s))Carcinogen Status:None of the components of this formulation are listed as a carcinogen by IARC, NTP or Vitro Bacterial Mutagenicity (Ames) Salmonella , E. coli NegativePage 5 of 714 Week(s) Rat Oral 200 mg/kg/day NOAEL No effects at maximum doseIn Vitro HGPRT Forward Gene Mutation Assay Chinese Hamster Ovary (CHO) cells NegativeRat Oral LD50 3000 mg/kgIn Vitro Unscheduled DNA Synthesis Rat Hepatocyte NegativeIn Vivo Chromosome Aberration Rat NegativeRevision date: 09-Mar-2014 ChlortetracyclineChlortetracyclineChlort etracycline2 Year(s) Rat Oral 700 mg/kg/day NOAEL Not carcinogenicMaterial Name: ChlorMax 502 Generation Reproductive Toxicity Rat Oral 500 mg/kg/day NOAEL Negative6 Week(s) Mouse Oral 100 mg/kg/day NOAEL No effects at maximum doseChlortetracycline14 Week(s) Mouse Oral 200 mg/kg/day NOAEL No effects at maximum doseChlortetracyclineVersion: SAFETY DATA SHEET_____11.

10 TOXICOLOGICAL INFORMATION12. ECOLOGICAL INFORMATIONE nvironmental Overview:Environmental properties have not been investigated. Releases to the environment should :No data availablePersistence and Degradability:No data availableBio-accumulative Potential:No data availableMobility in Soil:No data available13. DISPOSAL CONSIDERATIONSW aste Treatment Methods:Dispose of waste in accordance with all applicable laws and regulations. Member Statespecific and Community specific provisions must be considered. Considering the relevantknown environmental and human health hazards of the material, review and implementappropriate technical and procedural waste water and waste disposal measures to preventoccupational exposure and environmental release. It is recommended that waste minimizationbe practiced. The best available technology should be utilized to prevent environmentalreleases. This may include destructive techniques for waste and TRANSPORT INFORMATIONThe following refers to all modes of transportation unless specified regulated for transport under USDOT, EUADR, IATA, or IMDG REGULATORY INFORMATIONS afety, Health and Environmental Regulations/Legislation Specific for the Substance or MixtureCanada - WHMIS: ClassificationsWHMIS hazard class:Class D, Division 2, Subdivision A_____700101 Revision date: 09-Mar-2014 Material Name: ChlorMax 50 Version: 6 of 7 SAFETY DATA SHEET_____15.