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Search results with tag "Drug metabolism"

Pharmacokinetics/ADME In Drug Discovery

www.uab.edu

Sites of Drug Metabolism • The liver is the ppyrimary organ of drug metabolism. • The gastrointestinal tract is the most important extrahepatic site – Some orally administered drugs (e.g., isoproterenol) are conjugated extensively in the …

  Drug, Liver, Metabolism, The liver, In drug, Drug metabolism

Biotransformation of drugs (Drug metabolism )

www.fpharm.uniba.sk

Biotransformation of drugs takes place in two steps: first phase - functionalization reactions the molecule introduces a new functional group, usually polar (-COOH,-OH,-NH2) the polar group can serve as a reaction point for the second reaction phase second phase - conjugation reactions

  Phases, Drug, Metabolism, Biotransformation, Drug metabolism, Biotransformation of drugs

ROUTES OF DRUG ADMINISTRATION

technicaljournalsonline.com

liver via the portal vein • Irritation to gastric mucosa - nausea and vomiting • Destruction of drugs by gastric acid and digestive juices ... Drug Metabolism and Disposition,Vol. 25, 12. 3. Petri N, Bergman E, Forsell P, Hedeland M, Bondesson U, Knutson L

  Drug, Liver, Metabolism, Drug metabolism

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In Drug, Drug Metabolism, The liver, Biotransformation of drugs Drug metabolism, Biotransformation, Phase, DRUG, Liver