Search results with tag "Biotransformation"
Microbial Biotransformation: A Process for …
medcraveonline.comCitation: Smitha MS, Singh S, Singh R (2017) Microbial Biotransformation: A Process for Chemical Alterations. J Bacteriol Mycol Open Access 4(2): 00085. DOI: 10.15406/jbmoa.2017.04.00085 Microbial Biotransformation: A Process for Chemical …
BREVET PROFESSIONNEL PRÉPARATEUR EN ... - CFA Pharmacie
www.cfapharmacie.fr4.8 Citer l’organe principal impliqué dans les réactions de biotransformation. 4.9 Indiquer le terme général correspondant à la molécule obtenue par biotransformation. 4.10 Citer les deux voies principales d’éli mination des médicaments. 4.11 Indiquer l’autre classe pharmacologiqueégalement utilisée comme antisécrétoire
Spiriva HandiHaler - Food and Drug Administration
www.accessdata.fda.govBiotransformation The extent of biotransformation appears to be small. This is evident from a urinary excretion of 74% of unchanged substance after an intravenous dose to young healthy volunteers. Tiotropium, an ester, is nonenzymatically cleaved to the alcohol N-methylscopine and dithienylglycolic acid,
2章 药物代谢动力学 - ahmu.edu.cn
jcyxy.ahmu.edu.cnPhase I 药物 结合 药物 无活性 活性↑或↓ 药物 亲脂 亲水 排 泄 氧化、还原、水解引入或 脱去基团(-OH、-CH 3、-NH 2、-SH) Phase II 结合 结合 内源性葡萄糖苷酸、硫酸 、醋酸与药物或I期反应代 谢物结合 代谢步骤和方式 3. 代谢(metabolism, 生物转化, Biotransformation)
COMMITTEE AND THE COMMITTEE OF THE ... - European …
ec.europa.eu16 Liu et al. (2014), Microbial degradation of polyfluoroalkyl chemicals in the environment: a review. Butt et al. (2013), Biotransformation pathwayss of fluorotelomer-based polyfluoroalkyl substances: a review. 17 Kwiatkowski et al. (2020), Scientific basis to manage PFAS as a chemical class
Textile Dyes: Dyeing Process and Environmental Impact
cdn.intechopen.comDyeing Process and Environmental Impact Farah Maria Drumond Chequer, ... according to their application and chemical structure, and are composed of a group of atoms ... aryl amine derivatives generated during reductive biotransformation of the azo bond [22].
DRUG NAME: Oxaliplatin - BC Cancer
www.bccancer.bc.caMetabolism rapid nonenzymatic biotransformation to reactive platinum complexes7 active metabolite(s) DACH platinum species 6 inactive metabolite(s) several conjugates, 6: including the 1,2-DACH-platinum dichloride (2%) associated with neurotoxicity: 3:
Biotransformation: Phase I and Phase II Metabolism
www.edukesh.com• Biotransformation: The goal of biotransformation is to convert lipophilic chemicals to more polar ones so that they can be eliminated more easily from the body. Most of the time this results in changes in the pharmacological activity of a drug. Although we ordinarily think of drug metabolism as a process that inactivates
Biotransformation of drugs (Drug metabolism )
www.fpharm.uniba.skBiotransformation of drugs takes place in two steps: first phase - functionalization reactions the molecule introduces a new functional group, usually polar (-COOH,-OH,-NH2) the polar group can serve as a reaction point for the second reaction phase second phase - conjugation reactions