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ACG Clinical Guideline: Management of Crohn’s …

2018 by the American College of Gastroenterology The American Journal of GASTROENTEROLOGY481 Clinical guidelines INTRODUCTION Crohn s disease has been increasing in incidence and prevalence worldwide. At the same time, the number of therapeutic options is rapidly increasing. Th e purpose of this guideline is to review Crohn s disease Clinical features and natural history, diagnostics, and therapeutic interventions. To prepare this guideline, literature searches on the diff erent areas were conducted using Ovid MEDLINE from 1946 to 2018, EMBASE from 1988 to 2018, and SCOPUS from 1980 to 2018. Th e major terms that were searched were Crohn s disease, infl amma-tory bowel diseases (IBD), regional ileitis, and regional enteritis.

The American Journal of GASTROENTEROLOGY |

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