Transcription of LACTOSE MONOHYDRATE - uspbpep.com
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EUROPEAN PHARMACOPOEIA monohydrateBulkandtappeddensity( ). Determine the bulkdensity and the tapped density. Calculate the Hausner indexusing the following expression:V0=volume of bulk substance,Vf=volume of tapped substance. - LACTOSE and ( ).Silylation Rand 72 volumes ofpyridine solution. Dissolve about 1 mg of the substance to beexamined in ml ofdimethyl sulphoxide the silylation reagent. Mix gently and allow to stand for20 solution. Prepare a mixture of -lactosemonohydrate Rand - LACTOSE Rhaving an anomeric ratio ofabout 1:1 based on the labelled anomeric contents of the - LACTOSE MONOHYDRATE and - LACTOSE . Dissolve about 1 mgof this mixture in ml ofdimethyl sulphoxide ml of the silylation reagent.
Lactulose EUROPEAN PHARMACOPOEIA 5.0 C. Dissolve0.25gin5mlofwaterR.Add5mlofammoniaR and heat in a water-bath at 80 °C for 10 min. A red colour develops. D. It complies with the test for water …
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