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Lithium and serotonin function: implications for the ...

Psychopharmacology (1990) 100: 3-12 Psychopharmacology Springer-Vertag 1990 Review Lithium and serotonin function: implications for the serotonin hypothesis of depression Lawrence H. Price, Dennis S. Charney, Pedro L. Delgado, and George R. Heninger Clinical Neuroscience Research Unit, Ribicoff Research Facilities, Connecticut Mental Health Center, and Department of Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, CT 06508, USA Abstract. Lithium enjoys wide clinical use in the treatment of affective disorders, but the mechanism of its action in these conditions is still controversial. Recent studies have shown that Lithium can interact with other antidepressant drugs to enhance their efficacy, perhaps by specific effects on serotonin (5-HT) function.

Lithium and serotonin function: implications for the serotonin hypothesis of depression Lawrence H. Price, Dennis S. Charney, Pedro L. Delgado, and George R. Heninger Clinical Neuroscience Research Unit, Ribicoff Research Facilities, Connecticut Mental Health Center, and Department of Psychiatry, Yale University School of Medicine, 34 Park ...

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  Implications, Functions, Lithium, Serotonin, Implications for, Lithium and serotonin function

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