Transcription of Moxicam - Medicines
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Product Information Pg. 1 PRODUCT INFORMATION Moxicam Meloxicam NAME OF THE MEDICINE Active ingredient : Meloxicam Chemical name : 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazol yl)-2H-1,2-benzothiazine-3carboxamide-1, 1-dioxide Structural formula : Molecular formula : C14H13N3O4S2 Molecular weight : CAS Registry no. : 71125-38-7 DESCRIPTION Meloxicam is a pastel yellow solid with pKa values of and and a melting point of about 256 C. The substance is practically insoluble in water, soluble in dimethylformamide, slightly soluble in chloroform and acetone, and very slightly soluble in methanol. There are no chiral centres and no polymorphs are formed under normal conditions. Each Moxicam tablet consists of mg or 15 mg the active ingredient meloxicam and the following excipients: pregelatinized maize starch, microcrystalline cellulose, lactose monohydrate, maize starch, sodium citrate, colloidal anhydrous silica and magnesium stearate.
Moxicam – Product Information 2 of COX-1 activity), mouse macrophages (for testing for COX-2 activity), and human recombinant enzymes expressed in cos-cells and in human whole blood.
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