Transcription of PRODUCT INFORMATION - Medicines
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PRODUCT INFORMATION - Medicines
Version: bqpeliqu10118 Supersedes: bqpeliqu11117 Page 1 of 55 PRODUCT INFORMATION ELIQUIS apixaban NAME OF THE MEDICINE Apixaban, a selective inhibitor of the coagulation Factor Xa (FXa), is chemically described as 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopip eridin-1-yl)phenyl]-4,5,6,7-tetrahydro-1 H-pyrazolo[3,4-c]pyridine-3-carboxamide. Its molecular formula is C25H25N5O4, which corresponds to a molecular weight of Apixaban has the following structural formula: NNNH3 COH2 NOONO CAS Number: 503612-47-3 DESCRIPTION Apixaban is a white to pale yellow powder. At physiological pH ( ), apixaban does not ionize; its aqueous solubility across the physiological pH range is ~ mg/mL. The octanol/water partition coefficient is at pH ELIQUIS film-coated tablets are available for oral administration in strengths of mg and 5 mg apixaban with the following inactive ingredients: lactose, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
Version: bqpeliqu10118 Supersedes: bqpeliqu11117 Page 1 of 55 PRODUCT INFORMATION ELIQUIS® apixaban NAME OF THE MEDICINE Apixaban, a selective inhibitor of the coagulation Factor Xa (FXa), is chemically described as
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