Transcription of PRODUCT INFORMATION Valpro - Medicines
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PRODUCT INFORMATION Valpro Sodium valproate NAME OF THE MEDICINE Active ingredient : Sodium valproate Chemical name : Sodium di-n-propylacetic acid Structural formula : Molecular formula : C8H15O2Na Molecular weight : CAS Registry no. : 1069-66-5 DESCRIPTION Sodium valproate is a white, odourless, crystalline powder with a saline taste. It is quite dissimilar to other established anticonvulsants such as barbiturates, hydantoins, succinamides, oxazolidinediones and acetylureas in that it has no nitrogen or aromatic moiety. Each Valpro 200 tablet contains 200 mg sodium valproate. Each Valpro 500 tablet contains 500 mg sodium valproate. The tablets also contain the following excipients: maize starch, magnesium stearate, sodium starch glycollate, microcrystalline cellulose, colloidal anhydrous silica, purified talc, hypromellose, diethyl phthalate, cellacephate, macrogol 400, Opadry Violet OY-6721 (includes colours titanium dioxide CI 77891, indigo carmine CI 73015, erythrosine CI 45430, sunset yellow FCF CI 15985).
Valpro – Product Information 4 Patients known to have mitochondrial disorders caused by mutations in the nuclear gene encoding mitochondrial enzyme polymerase γ (POLG eg Alpers-Huttenlocher Syndrome) and in children under
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