Connected chromatography solutions

1 Connected chromatography solutions2019/2021 chromatography Consumables CatalogFind out more at 2019 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified. AD72973-EN 0419 SExpect reproducible results with sample prep, columns and vialsThe collective power of chromatographyMaximizing your chromatography productivity and achieving reproducible results requires optimizing the whole workflow from sample to knowledge. By choosing the right tools, from your sample preparation (manual or automated) to the highest selectivity column chemistry and cleanest vials, you maintain sample integrity and achieve the highest instrument efficiency and reduce the need for costly reanalysis. With the largest portfolio of sample handling; vials, plates and closures, column chemistries in a broad range of dimensions and sample preparation, we remain a steadfast and committed partner in your endeavor to improve the world around LAB SERVICESFind out more at PDF catalogue is designed to familiarise you with our comprehensive portfolio of chromatography consumables, columns and accessories, designed to deliver Connected chromatography solutions across Biopharma/Pharma, Food & Beverage, Environmental and Clinical workflows.

2 We have included key workflows in the next few pages to help with your product to use this PDF catalogYou can use the ctrl F function to search for products, applications, brands or part numbers, or you can navigate by section using the contents page to guide informationFor more information on chromatography consumables, to access application notes, educational resources, selection guides and product literature, please visit , for more information on our Instrumentation and key applications, please visit chromatography Consumables CatalogAppsLabGain access to our applications expertise on cloud-based Thermo Scientific AppsLab library of analytical applications for a comprehensive fully searchable method repository. Visit collaboration built for BiopharmaThe National Institute for Bioprocessing Research and Training (NIBRT) and Thermo Fisher Scientific are developing workflows using Thermo Fisher Scientific technology including the latest biomolecule columns.

3 For more information on collaboration built for BioPharma visit processingMass spectrometryUHPLCV ials & ClosuresLC columnsSample preparationThermo Scientific Biopharma workflow enablersCharge variants CX-1 pH Gradient Buffers MAbPac SCX LC Columns ProPac Elite WCX LC ColumnsAggregates MAbPac SEC and MAbPac HIC LC ColumnsIntact mass MAbPac RP LC Columns MAbPac SEC LC Columns ProPac Elite WCX LC Columns MAbPac SCX LC Columns MAbPac HIC LC ColumnsGlycan analysis GlycanPac LC Columns Accucore Amide HILIC LC ColumnsPeptide mapping SMART Digest Kits and SOLA Plates and Cartridges Accucore Vanquish C18 LC Columns Accucore 150 C18 LC Columns Hypersil GOLD C18 LC ColumnsBioanalysis large molecules SMART Digest IA Kits and SOLA Plates and Cartridges Accucore Vanquish C18 LC Columns Acclaim LC Columns Hypersil GOLD C18 LC ColumnsFind out more about consumables for your Biopharma workflow here Dattapppppppppppprrrrrooooooocccccccccee eeeeeeessssssssssssssssssssiiiiiiiiinnnn nnnngggggggggggggggMass spectrometryUHPLCSureStop Vials & ClosuresLC columnsGC columnsSample preparationThermo Scientific Pharmaceutical workflow enablersDiscovery DMPK HyperSep SPE Cartridges and Plates WebSeal Well Plates and Mats Accucore RP-MS LC Columns Accucore Biphenyl LC Columns Acclaim VANQUISH C18 UHPLC Columns Titan3 Syringe FiltersDevelopment DMPK / Pre Clinical SOLA /SOLA SPE Plates and Cartridges WebSeal Well Plates and Mats HyperSep SPE Cartridges and Plates Accucore C18 LC Columns Accucore Biphenyl LC Columns Hypersil GOLD VANQUISH C18 UHPLC Columns Clinical SOLA/SOLA SPE Plates and Cartridges WebSeal Well Plates and Mats Hypersil GOLD VANQUISH C18 UHPLC Columns Accucore C18 LC Columns Accucore Biphenyl LC Columns

4 QA/QC Titan3 Syringe Filters Hypersil GOLD C18 UHPLC Columns Accucore RP-MS LC Columns Accucore Biphenyl LC Columns TraceGOLD GC ColumnsDiscovery DMPK SMART Digest Kits WebSeal Well Plates and Mats MAbPac LC Columns ProPac Elite WCX LC Column GlycanPac LC Columns Acclaim 120 C18 Columns CX-1 pH Gradient BuffersSmall moleculesLarge moleculesDevelopment DMPK / Pre Clinical SMART Digest & SMART Digest ImmunoAffinity Kit SOLA/SOLA SPE Plates and Cartridges WebSeal Well Plates and Mats Acclaim 120 C18 ColumnsClinical SOLA/SOLA SPE Plates and Cartridges WebSeal Well Plates and Mats Acclaim 120 C18 ColumnsQA/QC Titan3 Syringe Filters SMART Digest Kits ProPac LC Columns MAbPac LC Columns CX-1 pH Gradient Buffers Acclaim 120 C18 ColumnsFind out more about consumables for your Pharmaceutical workflow here LData processingMass spectrometryUHPLCV ials & ClosuresLC columnsGC columnsSample preparationThermo Scientific Food and Beverage workflow enablersPesticides HyperSep SPE Cartridges QuEChERS Tr ace GOLD GC Columns GC Consumables and Accessories Accucore aQ LC Columns Acclaim Carbamate LC Columns Acclaim Trinity Q1 LC ColumnsContaminants by GC-MS HyperSep SPE Cartridges TraceGOLD GC Columns GC Consumables and AccessoriesMycotoxins HyperSep Retain Cartridges Accucore aQ LC Columns Hypersil GOLD LC ColumnsFood quality/ Food labelling / Food fraud HyperSep Retain Cartridges HyperSep SPE Cartridges Acclaim LC Columns Accucore LC Columns HyperREX LC Columns GC Columns and Consumables Veterinary drug residues QuEChERS Ta r g et 2 PTFE Syringe Filters Accucore VDX LC ColumnsFind out more about consumables for your Food & Beverage workflow here Data processingMass spectrometryUHPLC or GCVials & ClosuresLC or GC columnsSample

5 PreparationThermo Scientific Environmental workflow enablersPersistent Organic Pollutants (POP) HyperSep Cartridges TraceGOLD GC Columns LinerGOLD GC Liners BTO Septa GC Consumables and AccessoriesVolatile Organic Compounds (VOC) SPME Arrow TraceGOLD TG-VMS, TG-VRX, TG-624, TG-624 SilMS, TG-VVOC B, TRACE TR-V1, TR-524, and TracePLOT GC Columns LinerGOLD Liners BTO Septa GC Consumables and AccessoriesMicrocystins HyperSep Cartridges Hypersil GOLD aQ LC Columns Accucore C18 LC ColumnsSemi-Volatile Organic Compounds (SVOC) HyperSep Cartridges SPME Arrow TraceGOLD TG-XLBMS, TG-5 SilMS, TG-PAH, TG-XLBMS, TG-OCP, TG-OPP TR-Pesticide, and TR-8270 GC Columns LinerGOLD Liners BTO Septa GC Consumables and Accessories Find out more about consumables for your Environmental workflow here DDaattaapppppppppppprrrrrooooooooooooooc ccccccccceeeeeeeeeeessssssssssssssssssss ssssssssssiiiiiiiiinnnnnnnnggggggggggggg ggMass spectrometryUHPLCSureStop Vials & ClosuresLC columnsGC columnsSample preparationThermo Scientific Clinical research workflow enablersForensic toxicology SOLA /SOLA SPE Plates and Cartridges HyperSep SPE Cartridges and Plates HyperSep Retain Cartridges Accucore Biphenyl LC Columns Accucore RP-MS LC Columns Tr ace GOLD GC Columns and Guard ColumnsDrugs of abuse research SOLA/SOLA SPE Plates and Cartridges HyperSep Verify CX Cartridges Accucore Biphenyl LC Columns Hypersil GOLD LC Columns TraceGOLD GC Columns Supplement analysis HyperSep Retain Cartridges and Plates Hypercarb HPLC and

6 UHPLC Columns Hypersil GOLD PFP LC Columns Accucore aQ C18 LC Columns Amino acids, acylcarnitines, and succinylacetone research Hypersil GOLD C18 LC Columns Accucore aQ C18 LC Columns Acclaim HILIC LC Columns Titan3 Syringe Filters HyperSep SLE Plates and Cartridges TraceGOLD GC ColumnsTranslational proteomics SMART Digest Kits SOLA SPE Plates and Cartridges E ASY- Spr ay LC Columns PepMap RSLC Columns WebSeal Well Plates and MatsDrug monitoring research SOLA/SOLA SPE Plates and Cartridges WebSeal Well Plates and Mats Acclaim 120 C18 ColumnsFind out more about consumables for your Clinical workflow here Thermo Scientific GC columns and accessories are designed to give optimum system performance for today s challenging analyses. Thermo Scientific TraceGOLD , Thermo Scientific TRACE and Thermo Scientific TracePLOT columns provide excellent quality and performance.

7 Our range of GC accessories include all the tools needed by today s gas productsGC columns and accessoriesTraceGOLD GC columnsThe premium standard in GC column performance, delivering low bleed, excellent reproducibility and high levels of 5-034 LinerGOLD GC linersThe GOLD standard in GC liner performance, providing enhanced inertness, leading to increased accuracy and precision in analysis. Page 5-017 For more information, visit contentsGC columns and accessories Gas management 5-005 Syringes for GC instruments 5-008 Injection port septa 5-015 Injection port liners 5-017 Ferrules 5-022 Capillary accessories 5-025GC tools 5-030GC columns 5-033 TraceGOLD GC columns 5-034 TRACE GC columns 5-062 TracePLOT GC columns 5-074GC reagents 5-077 Reacti-Therm heating, stirring and evaporation system 5-089GC and GC-MS instruments 5-095GC derivatization reagentsMaking the undetectable detectable.

8 Thermo Scientific GC Derivatization reagents provide high levels of purity and reproducibility in analysis. Page 5-077 Reacti-Therm sample derivatization systemHeating, stirring and evaporation in a single system, offering a complete solution for derivatization and other small-scale reactions. Page 0895-0025-003GC columns and accessoriesProduct selection guideSelection of the correct GC columns and accessories is critical to ensure optimum system performance. The selection guide below is designed to simplify this processVials and closuresGC septaGC columnsGC ferrulesGC syringesGC linersThermo Scientific GC consumables are available for both Thermo Scientific and Agilent syringesSyringe selection by needle tip styleSyringe selection by needle gauge size Gauge is a measure of the thickness of the needle The higher the gauge number, the thinner the needle a 23 gauge is thicker than a 26 gauge Suffix s 23s refers to a needle with a narrower internal diameter For on-column injection ensure that the column ID is greater than the needle gaugeNeedle Tip StyleFeatures / Applications Cone (Tapered tip) Most versatile needle for autosampler use and resist coring of vial and inlet septa Bevel (Sharp tip) Typically used for manual injections.

9 The tip shape helps reduce septa coringSide Hole (Dome tip with a side hole for sample exit) Usually used for headspace and large volume injections Blunt End or 90 (flat top) Used for injectors that do not contain an inlet septa such as Merlin MicroSeal Dual Gauge Narrow gauge part suitable for megabore on-column injection. Wider part suitable for autosampler useGC linersMaterialUsesAdvantagesLimitations1 00% Graphite FID, NPD, high temperature Easy-to-use stable seal Higher temperature limit Can be easily removed Can be re-used Not for MS or oxygen- sensitive detectors Soft, easily deformed or destroyed Possible system contamination85% Vespel / 15% GraphiteMS and oxygen-sensitive detectors Long lifetime High temperature limit MS compatible Cannot be re-used Must be re-tightened after initial temperature cyclesThermo Scientific SilTite MS and oxygen-sensitive detectors Long lifetime High temperature limit MS compatible Cannot be re-used GC ferrulesVials and closuresGC columnsColumn ParameterParameters Affecting ResolutionPerformance ChangesEfficiencyRetentionSelectivityCol umn Length (m)

10 4 Doubling column length increases resolution by ~ 40%Internal Diameter (mm) 44 The smaller the column ID, the greater the efficiency and better the resolutionFilm Thickness ( m) 4 The thicker the film, the greater the retention, ideal for highly volatile compounds. The thinner the film, the sharper the peaks and lower the bleedStationary Phase Chemistry4 Altering the stationary phase can affect elution order and help separate closely, or co-eluting peaksMaterialMax Operating TemperatureKey FeaturesBTO400 C (330 C for 17 mm size) Low bleedTR-Green350 CLong lifetimeMarathon350 CHigh mechanical durabilityTR-Blue200 250 CEasy to penetrate for routine applicationsGC septa Nature of sampleVial Type RecommendedRoutine samplesClear glass (with or without patch) as SureStop 9mm screw thread or 11mm crimp vialLight sensitive samplesAmber glass (with or without patch) as SureStop 9mm screw thread or 11mm crimp vialLow volume samplesMicro-Inserts or Microsampling and High Recovery vials with fixed inserts or reduced internal volumeTrace levels Silanized glass and/or Certified KitsUltra Trace MS analysisMSCERT kits.