医学細菌学上重要なCorynebacterium属菌の検査法

1 2012 corynebacterium 207.. corynebacterium .. 24 8 17 . corynebacterium . Cory- nebacterium .. Key words: corynebacterium , . I.. corynebacterium 2012 8 list of corynebacterium . prokaryotic names with standing in nomenclature (LPSN) corynebacterium Coryne; . 110 11 bacterium; .. corynebacterium vaginale Arcanobacterium, Bre- Gardnerella vaginalis Coryne- vibacterium, Erysipelothrix, Dermabacter, Rothia, Micro- bacterium haemolyticum corynebacterium pyogenes bacterium, Turicella, Oerskovia, Curtobacterium.

2 Arcanobacterium C. pyogenes Ac- corynebacterium . tinomyces pyogenes corynebacterium equi . Rhodococcus equi, corynebacterium acnes Propi- . onibacterium acnes corynebacterium spp.. 1980 Arthrobacter, Clavibacter, Coryne- Curtobacterium Rhodococcus form bacteria .. 1980 . corynebacterium .. II. corynebacterium . corynebacterium 22 36 .. (m-DAP) . 296 8602 929 C. amycolatum, C. atypicum C. kroppenstedtii .. (C16 : TEL: 04 7099 2324 (DI). FAX: 04 7099 1196 0) (C18 : 1w9c) (C18 : 0). E-mail: (CFA) 1, 2.

3 Vol. 22 No. 3 2012. 1. 208 . (TBSA) C. urealyticum 5 . 37 18 1 . 2 mm .. 5 . (Lipophilic) Tween80 .. 2. C. ulcerans .. corynebacterium 2001 2 . C. ulcerans . C. diphtheriae, C. ulcerans, C. jeikeium, C. urea- 3 . lyticum, C. resistens, C. striatum, C. pseudodiphtheriti- 4 5 . cum, C. kroppenstedtii, C. amycolatum . 1 20 .. III. corynebacterium 5 37 24 . 1. C. diphtheriae group gravis, mitis, intermedius 1 2 mm .. 1990 C. diphtheriae . 1992 1999 . 68 1 21, 22 . 1999 . C. diphtheriae . C. ulcerans 3.

4 C. striatum . m, AIDS .. 6 10 . 5 37 24 . 1 mm . CNS . Coryneform bacteria .. 2 Vol. 22 No. 3 2012. corynebacterium 209. CAMP 8. C. riegelii 4. C. pseudodiphtheriticum 1998 Funke 27 .. 94 20 . 14 16 . 5 37 48 . 1 2 mm 5 . 37 24 . 48 mm . - .. 5. C. pseudotuberculosis 5 . C. diphtheriae .. 23, 24 9. C. jeikeium 1 . 1 25 . 5 37 24 . 1 mm 11 .. C. ulcerans CAMP 28, 29 Corynebacteri- um . 6. C. amycolatum .. 5 37 24 . 48 . C. xerosis, C. striatum, C. minutissimum mm . 1, 27 . 5 37 24 . 1 2 mm . - 10.

5 C. urealyticum . 30 . 7. C. minutissimum .. 1996 . 31 . 26 C. jeikeium . 5 37 24 5 37 . 1 mm 24 48 . mm .. Vol. 22 No. 3 2012. 3. 210 . API CO- 11. C. resistens RYNE . 2005 13 .. corynebacterium . 13, 29 36, 37, 39 .. C. jeikeium . 5 . 37 24 . 48 mm .. 5 10.. 12. C. kroppenstedtii .. 32, 33 2 19, 34 1 corynebacterium spp.. 5 . 37 24 mm . 48 mm 2.. 13. C. macginleyi . 29, 39 Ca, Mg . 5 . 35 35 24 48 48 . 5 24 . 37 24 mm 48 . 24 .. IV. corynebacterium .. 1. MIC (mini- mum inhibitory concentration).

6 Coryneform bacteria .. V.. corynebacterium .. RapID CB Plus system Corynebacte- 4 Vol. 22 No. 3 2012. 1. corynebacterium spp.. F CAMP.. O . C. diphtheriae F . biotype intermedius C. ulcerans F REV . C. striatum F V V . C. pseudodiphtheriticum O V . C. pseudotuberculosis F V V V REV . C. amycolatum F V V V V . C. minutissimum F V V . C. riegelii F V V ( ) . C. jeikeium O V . C. urealyticum O V . C. resistens F . C. kroppenstedtii F V . C. macginleyi F V . corynebacterium .. 1 V REV CAMP . Vol. 22 No.

7 3 2012. 5. 211. 212 . rium 14) Manzella, J. P., J. A. Kellogg, K. S. Parsey. 1995. Cory- nebacterium pseudodiphtheriticum a respiratory tract pathogen in adults. Clin. Infect. Dis., 20: 37 40.. 15) Ahmed, K., K. Kawakami, K. Watanabe, et al. 1995. corynebacterium pseudodiphtheriticum: a respiratory tract pathogen. Clin. Infect. Dis. 20: 41 46. 16) Freeman, J. D., H. J. Smith, H. G. Haines, et al. 1994. Seven patients with respiratory infections due to Co- rynebacterium pseudodiphtheriticum. Pathology 26.

8 311 314. 1) Funke, G., K. A. Bernard. 2011. Coryneform Gram- 17) 2000.. positive rods. p. 413 442, In: Manual of clinical mi- corynebacterium amycolatum IVH . crobiology 10th ed. (P. R. Murray, ed), American So- 1 10(1), 51 55 . ciety for Microbiology, Washington, 18) 2004.. 2) Funke, G., A. Graevenitz, J. E. Clarridge, et al. 1997.. Clinical microbiology of coryneform bacteria. Clin. 53: 22 27 . Microbiol. Rev. 10: 125 159. 19) 2012.. 3) Hatanaka, A., A Tsunoda, M. Okamoto, et al. 2003. corynebacterium kroppenstedtii.

9 corynebacterium ulcerans diphtheria in Japan. Emerg- 1 22(2): ing Infectious Diseases 9(6): 752 753. 161 166 . 4) 2006.. 20) Matsunami, M., O. Yoshihito, O. Kiyofumi, et al.. 2011. Urosepsis caused by Globicatella sanguinis and 1 IASR 27: 124 125 . corynebacterium riegelii in an adult: Case report and 5) 2008.. literature review J. Infect. Chemother., Online . FirstTM, 12 November . 1 82: 552 553. 21) 1998 . 6) 1997.. corynebacterium striatum . 1992 IASR 19(10), October. 46: 995 999 . 22) 1999 . 7) 1995.

10 IASR. corynebacterium striatum . 1 5(4): 22 26. 20(12), December. 8) Tarr, P. E., F. Stock, R. H. Cooke, et al. 2003. Multi- 23) Pascual, C., P. A. Lawson, J. A. Farrow, et al. 1995. drug-resistant corynebacterium striatum pneumonia Phylogenetic analysis of the genus corynebacterium in a heart transplant recipient. Transplant Infectious based on 16S rRNA gene sequences. Int. J. Syst. Bac- Disease 5: 53. teriol. 45: 724 728. 9) Prescott, P. L., A. F. Donald, Jr., A. S. Felix 2005. Co- 24) Ruimy, R.