ELECTRONIC CIGARETTES WHAT’S THE BOTTOM LINE?

1 CS298852-AELECTRONIC CIGARETTES what S THE BOTTOM LINE? E- CIGARETTES have the potential to benefit adult smokers who are notpregnant if used as a complete substitute for regular CIGARETTES andother smoked tobacco products. E- CIGARETTES are not safe for youth, young adults, pregnant women, oradults who do not currently use tobacco products. While e- CIGARETTES have the potential to benefit some people and harmothers, scientists still have a lot to learn about whether e- CIGARETTES areeffective for quitting smoking. If you ve never smoked or used other tobacco products or e- CIGARETTES ,don t ARE E- CIGARETTES ? E- CIGARETTES are known by many different names.

2 They are sometimes called e-cigs, e-hookahs, mods, vape pens, vapes, tank systems, and ELECTRONIC nicotine delivery systems. Some e- CIGARETTES are made to look like regular CIGARETTES , cigars, or pipes. Some resemble pens,USB sticks, and other everyday items. E- CIGARETTES produce an aerosol by heating a liquid that usually contains nicotine the addictivedrug in regular CIGARETTES , cigars, and other tobacco products flavorings, and other chemicalsthat help to make the aerosol. Users inhale this aerosol into their lungs. Bystanders can alsobreathe in this aerosol when the user exhales into the air. E- CIGARETTES can be used to deliver marijuana and other & ModsRechargeablee-cigaretteFor Print OnlyWHAT IS IN E-CIGARETTE AEROSOL?

3 THE E-CIGARETTE AEROSOL THAT USERS BREATHE FROM THE DEVICE AND EXHALE CAN CONTAIN HARMFUL AND POTENTIALLY HARMFUL SUBSTANCES:NICOTINEULTRAFINE PARTICLESFLAVORING SUCH AS DIACETYL, A CHEMICAL LINKED TO A SERIOUS LUNG DISEASECANCER-CAUSING CHEMICALSVOLATILE ORGANIC COMPOUNDSHEAVY METALS SUCH AS NICKEL, TIN, AND LEADIt is difficult for consumers to know what e-cigarette products contain. For example, some e- CIGARETTES marketed as containing zero percent nicotine have been found to contain E- CIGARETTES LESS HARMFUL THAN REGULAR CIGARETTES ?YES, but that doesn tmean e- CIGARETTES are safe. E-cigarette aerosol generally contains fewer toxicchemicals than the deadly mix of 7,000 chemicals insmoke from regular CIGARETTES .

4 However, e-cigaretteaerosol is not harmless. It can contain harmful andpotentially harmful substances, including nicotine,heavy metals like lead, volatile organic compounds,and cancer-causing agents. VSFor Print OnlyWHAT ARE THE HEALTH EFFECTS OF USING E- CIGARETTES ?SCIENTISTS ARE STILL LEARNING ABOUT THE LONG-TERM HEALTH EFFECTS OF E- CIGARETTES . HERE IS what WE KNOW e- CIGARETTES contain nicotine, which has known health effects Nicotine is highly addictive. Nicotine is toxic to developing fetuses. Nicotine can harm adolescent brain development,which continues into the early to mid-20s. Nicotine is a health danger for pregnant womenand their developing nicotine, e-cigarette aerosol can contain substances that harm the body.

5 This includes cancer-causing chemicals and tiny particlesthat reach deep into lungs. However, e-cigarette aerosolgenerally contains fewer harmful chemicals than smokefrom burned tobacco can cause unintended injuries. Defective e-cigarette batteries have caused fires andexplosions, some of which have resulted in seriousinjuries. In addition, acute nicotine exposure can be and adults have been poisoned by swallowing,breathing, or absorbing e-cigarette Print OnlyCAN E- CIGARETTES HELP ADULTS QUIT SMOKING CIGARETTES ?E- CIGARETTES ARE NOT CURRENTLY APPROVED BY THEFDA AS A QUIT SMOKING Preventive Services Task Force, a group of health experts that makes recommendations about preventive health care, concluded that the evidence is insufficient to recommend e- CIGARETTES for smoking cessation in adults, including pregnant , e-cigarettesmay help non-pregnant adult smokers if used as a complete substitute for all CIGARETTES and other smoked tobacco DATE, THE FEW STUDIES ON THE ISSUE ARE MIXED.

6 Evidence from two randomized controlled trials found that e- CIGARETTES with nicotine can help smokers stop smoking in the long term compared with placebo (non-nicotine) recent CDC study found that many adults are using e- CIGARETTES in an attempt to quit smoking. However, most adult e-cigarette users do not stop smoking CIGARETTES and are instead continuing to use both products ( dual use ). Because smoking even a few CIGARETTES a day can be dangerous, quitting smoking completely is very important to protect your Print OnlyWHO IS USING E- CIGARETTES ?E- CIGARETTES ARE THE MOST COMMONLY USED TOBACCO PRODUCT AMONG THE , YOUTH ARE MORE LIKELY THAN ADULTS TO USE E-CIGARETTEIn 2018, more than middle and high school students used e- CIGARETTES in the past 30 days, SCHOOL SCHOOL STUDENTSAMONG CURRENT E-CIGARETTE USERS AGED 45 YEARS AND OLDER in 2015, most were either current or former regular cigarette smokers, and had never been cigarette smokers.

7 IN CONTRAST, AMONG CURRENT E-CIGARETTE USERS AGED 18 24 YEARS, NEVER BEEN regular cigarette smokersIN 2015, AMONG ADULT E-CIGARETTE USERS current regular cigarette smokers never been regular cigarette former regular cigarette smokersIn 2017, adults were current e-cigarette usersFor Print Only