SAFETY DATA SHEET - Agilent

1 Conforms to US OSHA Hazard Communication SAFETY data SHEET . OPA Reagent, Part Number 5061- 3335 . Section 1. Identification Product identifier Product name : OPA Reagent, Part Number 5061- 3335 . Part no. : 5061- 3335 . Validation date : 4/30/2018. Relevant identified uses of the substance or mixture and uses advised against Material uses : Reagents and Standards for Analytical Chemistry Laboratory Use 6 x 1 ml ampoule Details of the supplier of the SAFETY data SHEET Supplier/Manufacturer : Agilent Technologies, Inc. 5301 Stevens Creek Blvd Santa Clara, CA 95051, USA. 800-227-9770. Emergency telephone number In case of emergency : CHEMTREC : 1-800-424-9300. Section 2. Hazards identification Classification of the substance or mixture OSHA/HCS status : This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR ).

2 Classification of the substance or mixture H290 CORROSIVE TO METALS - Category 1. H302 ACUTE TOXICITY (oral) - Category 4. H314 SKIN CORROSION - Category 1A. H318 SERIOUS EYE DAMAGE - Category 1. H317 SKIN SENSITIZATION - Category 1. H360 TOXIC TO REPRODUCTION (Fertility) - Category 1B. H360 TOXIC TO REPRODUCTION (Unborn child) - Category 1B. Ingredients of unknown : Percentage of the mixture consisting of ingredient(s) of unknown dermal toxicity: 10 - toxicity 30%. Percentage of the mixture consisting of ingredient(s) of unknown inhalation toxicity: 1 - 10%. GHS label elements Hazard pictograms : Signal word : Danger Hazard statements : H290 - May be corrosive to metals. H302 - Harmful if swallowed. H314 - Causes severe skin burns and eye damage. H317 - May cause an allergic skin reaction. H360 - May damage fertility or the unborn child.

3 Date of issue : 04/30/2018 1/15. OPA Reagent, Part Number 5061- 3335 . Section 2. Hazards identification Precautionary statements Prevention : P201 - Obtain special instructions before use. P202 - Do not handle until all SAFETY precautions have been read and understood. P280 - Wear protective gloves. Wear eye or face protection. Wear protective clothing. P234 - Keep only in original container. P261 - Avoid breathing vapor. P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. P272 (OSHA) - Contaminated work clothing must not be allowed out of the workplace. Response : P390 - Absorb spillage to prevent material damage. P308 + P313 - IF exposed or concerned: Get medical attention. P304 + P340 + P310 - IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER or physician.

4 P301 + P310 + P330 + P331 - IF SWALLOWED: Immediately call a POISON CENTER. or physician. Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353 + P363 + P310 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. Wash contaminated clothing before reuse. Immediately call a POISON CENTER or physician. P302 + P352 + P363 - IF ON SKIN: Wash with plenty of soap and water. Wash contaminated clothing before reuse. P333 + P313 - If skin irritation or rash occurs: Get medical attention. P305 + P351 + P338 + P310 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or physician. Storage : P405 - Store locked up. P406 - Store in a corrosion resistant container with a resistant inner liner.

5 Disposal : P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Supplemental label : Do not taste or swallow. Wash thoroughly after handling. elements Other hazards Hazards not otherwise : Causes digestive tract burns. classified Section 3. Composition/information on ingredients Substance/mixture : Mixture Ingredient name % CAS number Potassium hydroxide 10 1310-58-3. boric acid 5 10043-35-3. 3-Mercaptopropionic acid 3 107-96-0. Methanol <3 67-56-1. Phthalaldehyde 3 643-79-8. Potassium thiocyanate 3 333-20-0. Any concentration shown as a range is to protect confidentiality or is due to batch variation. There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

6 Occupational exposure limits, if available, are listed in Section 8. Date of issue : 04/30/2018 2/15. OPA Reagent, Part Number 5061- 3335 . Section 4. First aid measures Description of necessary first aid measures Eye contact : Get medical attention immediately. Call a poison center or physician. Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Continue to rinse for at least 10 minutes. Chemical burns must be treated promptly by a physician. Inhalation : Get medical attention immediately. Call a poison center or physician. Remove victim to fresh air and keep at rest in a position comfortable for breathing. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel.

7 It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours. Skin contact : Get medical attention immediately. Call a poison center or physician. Wash with plenty of soap and water. Remove contaminated clothing and shoes. Wash contaminated clothing thoroughly with water before removing it, or wear gloves. Continue to rinse for at least 10 minutes. Chemical burns must be treated promptly by a physician. In the event of any complaints or symptoms, avoid further exposure. Wash clothing before reuse.

8 Clean shoes thoroughly before reuse. Ingestion : Get medical attention immediately. Call a poison center or physician. Wash out mouth with water. Remove dentures if any. Remove victim to fresh air and keep at rest in a position comfortable for breathing. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Chemical burns must be treated promptly by a physician. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

9 Most important symptoms/effects, acute and delayed Potential acute health effects Eye contact : Causes serious eye damage. Inhalation : No known significant effects or critical hazards. Skin contact : Causes severe burns. May cause an allergic skin reaction. Ingestion : Harmful if swallowed. Corrosive to the digestive tract. Causes burns. Over-exposure signs/symptoms Eye contact : Adverse symptoms may include the following: pain watering redness Inhalation : Adverse symptoms may include the following: reduced fetal weight increase in fetal deaths skeletal malformations Skin contact : Adverse symptoms may include the following: pain or irritation redness blistering may occur reduced fetal weight increase in fetal deaths skeletal malformations Date of issue : 04/30/2018 3/15. OPA Reagent, Part Number 5061- 3335 . Section 4. First aid measures Ingestion : Adverse symptoms may include the following: stomach pains reduced fetal weight increase in fetal deaths skeletal malformations Indication of immediate medical attention and special treatment needed, if necessary Notes to physician : In case of inhalation of decomposition products in a fire, symptoms may be delayed.

10 The exposed person may need to be kept under medical surveillance for 48 hours. Specific treatments : No specific treatment. Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. Wash contaminated clothing thoroughly with water before removing it, or wear gloves. See toxicological information (Section 11). Section 5. Fire-fighting measures Extinguishing media Suitable extinguishing : Use an extinguishing agent suitable for the surrounding fire. media Unsuitable extinguishing : None known. media Special hazards arising from the substance or mixture Specific hazards arising : In a fire or if heated, a pressure increase will occur and the container may burst.