1,2-Dimethylindole-3-sulfonyl (MIS), the Most Acid- …
amino acid side chains are protected by trifluoroacetic acid (TFA)-labile protecting groups, usually tBu derivatives; and the C-terminal amino acid is anchored to the solid support through a TFA-labile
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Amino Acid-Protecting Groups - UB
diposit.ub.eduinvolve a carboxylic acid-protecting group which is removed upon amino protection and those that involve less reactive electrophiles on the reagent used to introduce the protecting group. An example of the former is the use of trimethylsilyl esters of amino acids prepared in
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